Affective prosody and facial expression cues differentially augment spoken sentence and discourse comprehension for acute left and right hemisphere stroke survivors. [PDF]
Tilton-Bolowsky VE +6 more
europepmc +1 more source
Somatic cell reprogramming for Parkinson's disease treatment
The fundamental purpose of cell reprogramming to treat Parkinson's disease is to generate dopaminergic neurons (DAN) and do transplantation. There are two ways to accomplish this. One method is to induce cells into induced DA neurons (iDAN) directly or to induce cells into induced pluripotent stem cells and ultimately into iDAN in vitro. Another option
Xiaozhuo Li, Kevin Fang, Fengping Wang
wiley +1 more source
Lactylation and N6-Methyladenosine RNA modification in neuropsychiatric sequelae after intracerebral hemorrhage: a hypothesis-generating metabolic-glial-circuit framework. [PDF]
Chen W +7 more
europepmc +1 more source
This expert consensus proposes a patient‐centered pathway for functional reconstruction after post‐stroke spastic hemiplegia: “patient goal–pathophysiologic component–treatment target–functional reassessment.” Treatment selection and sequencing across motor retraining, brain–computer interfaces, peripheral nerve surgery, and tendon/soft‐tissue ...
Peng Wen +39 more
wiley +1 more source
Response letter: net water uptake and lesion extent as joint expressions of ischaemic injury: a comment on the TENSION secondary analysis. [PDF]
Broocks G, Meyer L, Kniep HC.
europepmc +1 more source
The Endothelial CXCR Family in Vascular Health and Disease
ABSTRACT Endothelial cells (ECs) form the dynamic interface between blood and tissue, serving as key regulators of vascular homeostasis, inflammation, and repair. Among the molecular systems governing endothelial behavior, the C‐X‐C motif chemokine receptor (CXCR) family—originally characterized in immunology for its roles in leukocyte trafficking and ...
Zhiming Wu +4 more
wiley +1 more source
Symptom Network and Lesion Mapping of Post-Stroke Depression, Cognitive Impairment, and Dysfunction: A Multicenter Cohort Study. [PDF]
Du Q +6 more
europepmc +1 more source
ABSTRACT It is estimated that a large proportion of drug candidates fail in human clinical trials, mainly because animal models cannot fully replicate human disease and because of differential responses to various medications between humans and animals.
Weiping Ding, Iqra Ilyas, Suowen Xu
wiley +1 more source
Cognition in Cardiovascular Disease. [PDF]
Salardini A, Azarbar S.
europepmc +1 more source
Metrnl: A Novel Therapeutic Target in Atherosclerosis
ABSTRACT Atherosclerosis is a chronic inflammatory vascular disease and the main pathological basis of cardiovascular and cerebrovascular events. Exploration of endogenous protective factors in the disease is beneficial for the establishment of new therapeutic strategies.
Pin Wang, Dao‐Xin Wang, Chao‐Yu Miao
wiley +1 more source

