Results 71 to 80 of about 313,405 (294)
Molecular Study of Interactions between Hematopoietic Stem Cells and Stromal Cells [PDF]
, 2002 Multipotent hematopoietic stem cells (HSCs) are progenitors of all types of hematopoietic cells, and the efficient isolation and propagation of HSCs will significantly enhance our ability to manage many human disorders with bone marrow transplantation ...
Heard, Amanda +8 more
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In vitro localization of bone growth factors in constructs of biodegradable scaffolds seeded with marrow stromal cells and cultured in a flow perfusion bioreactor [PDF]
, 2006 Tissue engineering strategies aim at controlling the behavior of individual cells to stimulate tissue formation. This control is achieved by mimicking signals that manage natural tissue development or repair.
Bossano, C. M. +4 more
core +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Neuropsychiatric Disease and Treatment, 2020 Babak Kashefi,1 Mehdi Mohammadi,2 Farzin Rezaei,1 Narges Ghadami,1 Khashaiar Jalili,3 Ali Jalili2 1Neurosciences Research Center, Research Institute for Health Development, Kurdistan University of Medical Sciences, Sanandaj, Iran; 2Cancer and Immunology ...
Kashefi B +5 more
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RIPK4 function interferes with melanoma cell adhesion and metastasis
Molecular Oncology, EarlyView.RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
Journal of Biomedical Science, 2012 Background The CXC chemokine ligand 12 (CXCL12)/stromal cell-derived factor-1 (SDF-1) and CXC receptor 4 (CXCR4) axis is involved in human colorectal cancer (CRC) carcinogenesis and can promote the progression of CRC.
Tung Shui-Yi +7 more
doaj +1 more source
Targeting the CXCR4 pathway using a novel anti-CXCR4 IgG1 antibody (PF-06747143) in chronic lymphocytic leukemia. [PDF]
, 2017 BackgroundThe CXCR4-CXCL12 axis plays an important role in the chronic lymphocytic leukemia (CLL)-microenvironment interaction. Overexpression of CXCR4 has been reported in different hematological malignancies including CLL.
Amaya-Chanaga, Carlos I +18 more
core +4 more sources
Role of stromal cell-derived factor-1 alpha on endochondral ossification [PDF]
Osteoarthritis and Cartilage, 2012 s / Osteoarthritis and Cartilage 20 (2012) S10–S53 S44 Sost mRNA suggesting that Sclerostin might be regulated by Wnt. We further observed an enhanced expression of Sclerostin in osteoarthritic cartilage compared to cartilage of control mice. Conclusions:We here show that Wnt3a increases the catabolic activity and inhibits the anabolic activity in ...
Kim, G. +5 more
openaire +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Политико-правовые проблемы, пути развития украино-российских отношений [PDF]
, 2009 Aim of the study was to investigate the effect of catheter-based transendocardial delivery of stromal cell-derived factor 1 alpha on left ventricular function in a porcine model of myocardial infarction. In domestic pigs myocardial infarction was induced
Шеховцов, Андрей Николаевич
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