Results 71 to 80 of about 313,405 (295)
In vitro localization of bone growth factors in constructs of biodegradable scaffolds seeded with marrow stromal cells and cultured in a flow perfusion bioreactor [PDF]
, 2006 Tissue engineering strategies aim at controlling the behavior of individual cells to stimulate tissue formation. This control is achieved by mimicking signals that manage natural tissue development or repair.
Bossano, C. M. +4 more
core +1 more source
Stromal cell-derived factor-1 enhances pro-angiogenic effect of granulocyte-colony stimulating factor [PDF]
Cardiovascular Research, 2007 Granulocyte colony-stimulating factor (G-CSF) mobilizes bone marrow mononuclear cells into the peripheral circulation. Stromal cell-derived factor-1 (SDF-1) enhances the homing of progenitor cells mobilized from the bone marrow and augments neovascularization in ischemic tissue.
Yaohong, Tan +8 more
openaire +2 more sources
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Neuropsychiatric Disease and Treatment, 2020 Babak Kashefi,1 Mehdi Mohammadi,2 Farzin Rezaei,1 Narges Ghadami,1 Khashaiar Jalili,3 Ali Jalili2 1Neurosciences Research Center, Research Institute for Health Development, Kurdistan University of Medical Sciences, Sanandaj, Iran; 2Cancer and Immunology ...
Kashefi B +5 more
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A highly efficacious lymphocyte chemoattractant, stromal cell-derived factor 1 (SDF-1) [PDF]
The Journal of experimental medicine, 1996 Chemotactic factors are postulated to direct emigration of lymphocytes from the blood stream into sites of inflammation. Members of a family of chemotactic cytokines, termed chemokines, have been shown to attract lymphocytes but efficacy, i.e., the maximal percentage of attracted cells, has been low.
BLEUL CC +4 more
openaire +3 more sources
RIPK4 function interferes with melanoma cell adhesion and metastasis
Molecular Oncology, EarlyView.RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
Journal of Biomedical Science, 2012 Background The CXC chemokine ligand 12 (CXCL12)/stromal cell-derived factor-1 (SDF-1) and CXC receptor 4 (CXCR4) axis is involved in human colorectal cancer (CRC) carcinogenesis and can promote the progression of CRC.
Tung Shui-Yi +7 more
doaj +1 more source
Targeting the CXCR4 pathway using a novel anti-CXCR4 IgG1 antibody (PF-06747143) in chronic lymphocytic leukemia. [PDF]
, 2017 BackgroundThe CXCR4-CXCL12 axis plays an important role in the chronic lymphocytic leukemia (CLL)-microenvironment interaction. Overexpression of CXCR4 has been reported in different hematological malignancies including CLL.
Amaya-Chanaga, Carlos I +18 more
core +4 more sources
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Политико-правовые проблемы, пути развития украино-российских отношений [PDF]
, 2009 Aim of the study was to investigate the effect of catheter-based transendocardial delivery of stromal cell-derived factor 1 alpha on left ventricular function in a porcine model of myocardial infarction. In domestic pigs myocardial infarction was induced
Шеховцов, Андрей Николаевич
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