Results 71 to 80 of about 1,337,681 (248)

Pruning based Distance Sketches with Provable Guarantees on Random Graphs

, 2019
Measuring the distances between vertices on graphs is one of the most fundamental components in network analysis. Since finding shortest paths requires traversing the graph, it is challenging to obtain distance information on large graphs very quickly ...
Goel, Ashish, Yu, Huacheng, Zhang, Hongyang   +2 more
core   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Human-Induced Landscape Changes Homogenize Atlantic Forest Bird Assemblages through Nested Species Loss.

PLoS ONE, 2016
The increasing number of quantitative assessments of homogenization using citizen science data is particularly important in the Neotropics, given its high biodiversity and ecological peculiarity, and whose communities may react differently to landscape ...
Marcelo Alejandro Villegas Vallejos, André Andrian Padial, Jean Ricardo Simões Vitule   +2 more
doaj   +1 more source

Adverse drug reactions of antihypertensive agents at tertiary care hospital in central Nepal

Journal of College of Medical Sciences-Nepal, 2017
Background & Objectives: Acute Hypertension is the most common condition seen in primary care and leads to myocardial infarction, stroke, renal failure, and death if not detected early and treated appropriately.
Sabita Paudel, M Sudarsana Chetty, Shankar Laudari, Nuwadatta Subedi   +3 more
doaj   +1 more source

Estimation of Magnetic Field Strength in the Turbulent Warm Ionized Medium [PDF]

, 2009
We studied Faraday rotation measure (RM) in turbulent media with the rms Mach number of unity, using isothermal, magnetohydrodynamic turbulence simulations. Four cases with different values of initial plasma beta were considered. Our main findings are as
Balsara, Berkhuijsen, Burkhart, Crutcher, Dongsu Ryu, Haffner, Han, Han, Han, Haverkorn, Heiles, Hill, Jongsoo Kim, Jungyeon Cho, Kim, Larson, Mac Low, Mac Low, Ostriker, Padoan, Paul Alexander, Qingwen Wu, Spitzer, Stone, Tufte   +24 more
core   +2 more sources

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Neutrino oscillation constraints on neutrinoless double beta decay [PDF]

, 1997
We have studied the constraints imposed by the results of neutrino oscillation experiments on the effective Majorana mass || that characterizes the contribution of Majorana neutrino masses to the matrix element of neutrinoless double-beta decay.
A. Faessler, A. Yu. Smirnov, A.I. Belesev, B. Achkar, B.T. Cleveland, C. Athanassopoulos, C. Athanassopoulos, C. Giunti, C. W. Kim, C. Weinheimer, D.O. Caldwell, D.O. Caldwell, E. Ma, E. Ma, E.J. Chun, F. Boehm, F. Simkovic, G. Fiorentini, G. Pantis, G. Raffelt, G.L. Fogli, G.L. Fogli, G.S. Vidyakin, H. Minakata, J. Hellmig, J. Pantaleone, J.J. Gomez-Cadenas, J.N. Abdurashitov, J.N. Bahcall, J.N. Bahcall, J.R. Primack, J.T. Peltoniemi, K. Daum, K.S. Babu, K.S. Babu, K.S. Hirata, L. Borodovsky, M Günther, M. Aglietta, M. Doi, M. Gell-Mann, M. Hirsch, M. Hirsch, M. Hirsch, M. Hirsch, M. Hirsch, M. Hirsch, M. Hirsch, M. Hirsch, M. Moe, M. Monteno, N. Hata, N. Hata, N. Okada, O. Panella, P. Anselmann, P.I. Krastev, P.I. Krastev, P.I. Krastev, R. Foot, R.M. Barnett, S. Goswami, S. M. Bilenky, S. Turck-Chièze, S. Weinberg, S.M. Bilenky, S.M. Bilenky, S.M. Bilenky, S.M. Bilenky, S.M. Bilenky, S.T. Petcov, T. Yanagida, V. Barger, V. Berezinsky, V. Castellani, V. Castellani, W. Hampel, W.W.M. Allison, X. Shi, Y. Fukuda, Z. Berezhiani   +80 more
core   +2 more sources

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

Exogenous Ghrelin Increases Plasma Insulin Level in Diabetic Rats

Biomolecules, 2020
Ghrelin, a 28-amino acid peptide, is a strong growth hormone secretagogue and a regulator of food intake. In addition, ghrelin is thought to play a role in insulin secretion and in glucose homeostasis.
Haba Elabadlah, Rasheed Hameed, Crystal D’Souza, Sahar Mohsin, Ernest A. Adeghate   +4 more
doaj   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source