Results 81 to 90 of about 2,919,635 (295)
Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Unit-free strongly commuting Regular Rings [PDF]
In this paper, ring R satisfying in the condition xy = (yx)2a(yx)2 for all x; y 2 R n U with some a in R and is called Unit-free strongly commuting Regular Rings. We observe the structure of a Unit-free strongly commuting regular ring.
Sabet, Shabanali Safari +1 more
core
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Fuzzy $e$-regular spaces and strongly $e$-irresolute mappings [PDF]
The aim of this paper is to introduce fuzzy ($e$, almost) $e^{*}$-regular spaces in $check{S}$ostak's fuzzy topological spaces. Using the $r$-fuzzy $e$-closed sets, we define $r$-($r$-$theta$-, $r$-$etheta$-) $e$-cluster points and their properties ...
Veerappan Chandrasekar +1 more
doaj +1 more source
Prospecting the protein design landscape
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source
Disconnecting strongly regular graphs
In this paper, we show that the minimum number of vertices whose removal disconnects a connected strongly regular graph into non-singleton components, equals the size of the neighborhood of an edge for many graphs. These include blocks graphs of Steiner $2$-designs, many Latin square graphs and strongly regular graphs whose intersection parameters are ...
Sebastian M. Cioaba +2 more
openaire +4 more sources
Metastatic niche shaped by host factors influences disseminated cancer cell fate
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
Strongly Regular Extensions of Rings [PDF]
As defined by Arens and Kaplansky [2] a ring A is strongly regular (s.r.) in case to each a∊ A there corresponds x = xa ∊A depending on a such that a 2 x = a. In the present article a ring A is defined to be a s.r.
openaire +2 more sources
Hamiltonian Strongly Regular Graphs [PDF]
We give a sufficient condition for a distance-regular graph to be Hamiltonian. In particular, the Petersen graph is the only connected non-Hamiltonian strongly regular graph on fewer than 99 vertices.Distance-regular graphs;Hamilton cycles JEL ...
Brouwer, A.E., Haemers, W.H.
core
Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis
This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng +8 more
wiley +1 more source

