Results 51 to 60 of about 7,800 (264)

Development and Psychometric Analysis of the Student-Teacher Relationship Scale - Short Form

open access: yesFrontiers in Psychology, 2015
The purpose of this study is the construction and validation of an Italian Short Form version of the Student-Teacher Relationship Scale (Pianta 2001; STRS-SF) in the Italian educational setting for 1256 Students and 210 teachers.
Michele eSettanni   +4 more
doaj   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Dinucleotide (CA)n tandem repeats on the human X-chromosome and the history of the Mediterranean populations

open access: yesAnnals of Human Biology, 2018
Background: Tandem repeats (STRs) are genomic markers of particular interest in forensic and population genetics. Most of the population data currently available correspond to the variation of STRs of forensic panels, which barely include dinucleotide ...
Josep Santamaría   +4 more
doaj   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

A systematic evaluation of short tandem repeats in lipid candidate genes: riding on the SNP-wave.

open access: yesPLoS ONE, 2014
Structural genetic variants as short tandem repeats (STRs) are not targeted in SNP-based association studies and thus, their possible association signals are missed.
Claudia Lamina   +11 more
doaj   +1 more source

Assessment of the forensic application of 50 Y-STR markers in a large pedigree

open access: yesForensic Sciences Research, 2020
Short tandem repeats on the Y chromosome (Y-STRs), characterized by paternal inheritance, are valuable in forensic practice. Notably, the potential application of Y-STRs in pedigrees should be drawn upon, especially in China’s surname-concentrated ...
Yi Ye   +5 more
doaj   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

Application of X-STRs for Forensic Identification in Mixed DNA Profile: A Case Report

open access: yesForensic Sciences
Autosomal polymorphisms (STRs) or Y-Chromosome polymorphisms (Y-STRs) are usually used for the study and deconvolution of mixed DNA profiles in forensic genetics, accompanying data interpretation with biostatistical evaluations (e.g., RMP, RMNE, LR ...
Nunzia Ilaria Vacca   +4 more
doaj   +1 more source

Genome-wide detection of short tandem repeat expansions by long-read sequencing

open access: yesBMC Bioinformatics, 2020
Background Short tandem repeat (STR), or “microsatellite”, is a tract of DNA in which a specific motif (typically 
Qian Liu, Yao Tong, Kai Wang
doaj   +1 more source

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