Results 1 to 10 of about 93,830 (117)

Comparative synthesis of tandem repeats in the control region of Epinephelus mitogenomes (Peciformes: Epinephelidae) [PDF]

Genetics and Molecular Biology
In this study, we analyzed the evolutionary patterns of tandem repeats in the mitochondrial Control Region (CR) of groupers of the genus Epinephelus.
Carla Bessa-Brito, Rodrigo Petry Corrêa de Sousa, Wanny Gomes de Lima, Renata Furtado do Rosário, Luan Pinto Rabelo, Yrlan Sousa Oliveira, Iracilda Sampaio, Grazielle Fernanda Evangelista Gomes, Marcelo Vallinoto   +8 more
doaj   +3 more sources

Diverse short tandem repeat sequences influence gene regulation in human populations [PDF]

Genome Biology
Background Short tandem repeat (STR) length is a known determinant of pathogenicity in a variety of human disorders. The repeat sequence itself can modulate disease severity and penetrance; however, the broader impact of STR sequence variation on gene ...
Aleksandra Mitina, Worrawat Engchuan, Brett Trost, Giovanna Pellecchia, Stephen W. Scherer, Ryan K. C. Yuen   +5 more
doaj   +2 more sources

Short Tandem Repeat-Enriched Architectural RNAs in Nuclear Bodies: Functions and Associated Diseases

Non-Coding RNA, 2020
Nuclear bodies are membraneless, phase-separated compartments that concentrate specific proteins and RNAs in the nucleus. They are believed to serve as sites for the modification, sequestration, and storage of specific factors, and to act as ...
Kensuke Ninomiya, Tetsuro Hirose
doaj   +3 more sources

Assembly and Characterization of the Mitochondrial Genome of Fallopia aubertii (L. Henry) Holub

Frontiers in Bioscience-Landmark, 2023
Background: Fallopia aubertii (L. Henry) Holub is a perennial semi-shrub with both ornamental and medicinal value. The mitochondrial genomes of plants contain valuable genetic traits that can be utilized for the exploitation of genetic resources.
Xin Zhang, Yong-Chang Lu, Jiu-Li Wang
doaj   +1 more source

The Singular Evolution of Olea Genome Structure

Frontiers in Plant Science, 2022
The current view of plant genome evolution proposes that genome size has mainly been determined by polyploidisation and amplification/loss of transposons, with a minor role played by other repeated sequences, such as tandem repeats.
Flavia Mascagni, Elena Barghini, Marilena Ceccarelli, Luciana Baldoni, Carlos Trapero, Carlos Trapero, Concepción Muñoz Díez, Lucia Natali, Andrea Cavallini, Tommaso Giordani   +9 more
doaj   +1 more source

Immune activation by a multigene family of lectins with variable tandem repeats in oriental river prawn (Macrobrachium nipponense) [PDF]

Open Biology, 2020
Genomic regions with repeated sequences are unstable and prone to rapid DNA diversification. However, the role of tandem repeats within the coding region is not fully characterized.
Ying Huang, Xin Huang, Xuming Zhou, Jialin Wang, Ruidong Zhang, Futong Ma, Kaiqiang Wang, Zhuoxing Zhang, Xiaoling Dai, Xueying Cao, Chao Zhang, Keke Han, Qian Ren   +12 more
doaj   +1 more source

Structural characteristics of a mitochondrial control region from Myotis bat (Vespertilionidae) mitogenomes based on sequence datasets

Data in Brief, 2019
The datasets included sequences of a control region from Myotis bat mitogenomes. The control region (1706–2005 bp) of the Myotis mitogenomes was divided into three domains similar to that of other mammals, which included the common conserved blocks (ETAS
Md M. Rahman, Kwang B. Yoon, Yung C. Park   +2 more
doaj   +1 more source

Genome-wide survey of tandem repeats by nanopore sequencing shows that disease-associated repeats are more polymorphic in the general population

BMC Medical Genomics, 2021
Background Tandem repeats are highly mutable and contribute to the development of human disease by a variety of mechanisms. It is difficult to predict which tandem repeats may cause a disease.
Satomi Mitsuhashi, Martin C. Frith, Naomichi Matsumoto   +2 more
doaj   +1 more source

Reconstructing the history of a WD40 beta-propeller tandem repeat using a phylogenetically informed algorithm [PDF]

PeerJ Computer Science, 2015
Tandem repeat sequences have been found in great numbers in proteins that are conserved in a wide range of living species. In order to reconstruct the evolutionary history of such sequences, it is necessary to develop algorithms and methods that can work
Philippe Lavoie-Mongrain, Mahdi Belcaid, Aïda Ouangraoua, Anne Bergeron, Guylaine Poisson   +4 more
doaj   +2 more sources

Estimation of duplication history under a stochastic model for tandem repeats

BMC Bioinformatics, 2019
Background Tandem repeat sequences are common in the genomes of many organisms and are known to cause important phenomena such as gene silencing and rapid morphological changes. Due to the presence of multiple copies of the same pattern in tandem repeats
Farzad Farnoud, Moshe Schwartz, Jehoshua Bruck   +2 more
doaj   +1 more source