Results 41 to 50 of about 177,651 (293)
Nanopore Sequencing Resolves Elusive Long Tandem-Repeat Regions in Mitochondrial Genomes [PDF]
International Journal of Molecular Sciences, 2021 Long non-coding, tandem-repetitive regions in mitochondrial (mt) genomes of many metazoans have been notoriously difficult to characterise accurately using conventional sequencing methods. Here, we show how the use of a third-generation (long-read) sequencing and informatic approach can overcome this problem.
Liina Kinkar +8 more
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RNA biology of disease-associated microsatellite repeat expansions
Acta Neuropathologica Communications, 2017 Microsatellites, or simple tandem repeat sequences, occur naturally in the human genome and have important roles in genome evolution and function. However, the expansion of microsatellites is associated with over two dozen neurological diseases. A common
Kushal J. Rohilla, Keith T. Gagnon
doaj +1 more source
The mitochondrial genome of the venomous cone snail conus consors [PDF]
, 2012 Cone snails are venomous predatory marine neogastropods that belong to the species-rich superfamily of the Conoidea. So far, the mitochondrial genomes of two cone snail species (Conus textile and Conus borgesi) have been described, and these feed on ...
Baden-Tillson, Holly +9 more
core +3 more sources
IMPACT OF TANDEM REPEATS ON THE SCALING OF NUCLEOTIDE SEQUENCES [PDF]
International Journal of Bifurcation and Chaos, 2006 Techniques such as detrended fluctuation analysis (DFA) and its extensions have been widely used to determine the nature of scaling in nucleotide sequences. In this brief communication we show that tandem repeats which are ubiquitous in nucleotide sequences can prevent reliable estimation of possible long-range correlations. Therefore, it is important
Nagarajan, Radhakrishnan +1 more
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Molecular cytogenetic characterisation of Salix viminalis L. using repetitive DNA sequences [PDF]
, 2013 Salix viminalis L. (2n=38) is a diploid dicot species belonging to the Salix genus of the Salicaceae family. This short-rotation woody crop is one of the most important renewable bioenergy resources worldwide.
Dudits, Dénes +3 more
core +1 more source
Chickens possess centromeres with both extended tandem repeats and short non-tandem-repetitive sequences [PDF]
Genome Research, 2010 The centromere is essential for faithful chromosome segregation by providing the site for kinetochore assembly. Although the role of the centromere is conserved throughout evolution, the DNA sequences associated with centromere regions are highly divergent among species and it remains to be determined how centromere DNA directs kinetochore formation ...
Wei-Hao, Shang +7 more
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Intragenic tandem repeat variation between
BMC Microbiology, 2008 Background Bacterial genomes harbour a large number of tandem repeats, yet the possible phenotypic effects of those found within the coding region of genes are only beginning to be examined.
Jarraud Sophie +5 more
doaj +1 more source
Bio-Protocol, 2022 Repeat expansion diseases, including fragile X syndrome, Huntington’s disease, and C9orf72-related motor neuron disease and frontotemporal dementia, are a group of disorders associated with polymorphic expansions of tandem repeat nucleotide sequences ...
Joanne Sharpe, Nikki Harper, Ryan West
doaj +1 more source
Intragenic tandem repeats in : structure, function and distribution [PDF]
, 2009 Background Expressed sequence tag (EST) databases provide a valuable source of genetic data in organisms whose genome sequence information is not yet compiled.
Colson, I. +2 more
core +2 more sources
The Role of Retrotransposons in Gene Family Expansions: Insights from the Mouse \u3ci\u3eAbp\u3c/i\u3e Gene Family [PDF]
, 2013 Background: Retrotransposons have been suggested to provide a substrate for non-allelic homologous recombination (NAHR) and thereby promote gene family expansion. Their precise role, however, is controversial.
Janoušek, Václav +2 more
core +2 more sources