Results 31 to 40 of about 90,014 (157)
RNA biology of disease-associated microsatellite repeat expansions
Acta Neuropathologica Communications, 2017 Microsatellites, or simple tandem repeat sequences, occur naturally in the human genome and have important roles in genome evolution and function. However, the expansion of microsatellites is associated with over two dozen neurological diseases. A common
Kushal J. Rohilla, Keith T. Gagnon
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Intragenic tandem repeat variation between
BMC Microbiology, 2008 Background Bacterial genomes harbour a large number of tandem repeats, yet the possible phenotypic effects of those found within the coding region of genes are only beginning to be examined.
Jarraud Sophie +5 more
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Bio-Protocol, 2022 Repeat expansion diseases, including fragile X syndrome, Huntington’s disease, and C9orf72-related motor neuron disease and frontotemporal dementia, are a group of disorders associated with polymorphic expansions of tandem repeat nucleotide sequences ...
Joanne Sharpe, Nikki Harper, Ryan West
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Tandem repeats finder: a program to analyze DNA sequences [PDF]
Nucleic Acids Research, 1999 A tandem repeat in DNA is two or more contiguous, approximate copies of a pattern of nucleotides. Tandem repeats have been shown to cause human disease, may play a variety of regulatory and evolutionary roles and are important laboratory and analytic tools. Extensive knowledge about pattern size, copy number, mutational history, etc. for tandem repeats
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Sunflower centromeres consist of a centromere-specific LINE and a chromosome-specific tandem repeat
Frontiers in Plant Science, 2015 The kinetochore is a protein complex including kinetochore-specific proteins that plays a role in chromatid segregation during mitosis and meiosis. The complex associates with centromeric DNA sequences that are usually species-specific. In plant species,
Kiyotaka eNagaki +4 more
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Straglr: discovering and genotyping tandem repeat expansions using whole genome long-read sequences
Genome Biology, 2021 Tandem repeat (TR) expansion is the underlying cause of over 40 neurological disorders. Long-read sequencing offers an exciting avenue over conventional technologies for detecting TR expansions.
Readman Chiu +3 more
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Evolution of Tandem Repeats Is Mirroring Post-polyploid Cladogenesis in Heliophila (Brassicaceae)
Frontiers in Plant Science, 2021 The unigeneric tribe Heliophileae encompassing more than 100 Heliophila species is morphologically the most diverse Brassicaceae lineage. The tribe is endemic to southern Africa, confined chiefly to the southwestern South Africa, home of two biodiversity
Mert Dogan +16 more
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Finding the region of pseudo-periodic tandem repeats in biological sequences [PDF]
Algorithms for Molecular Biology, 2006 The genomes of many species are dominated by short sequences repeated consecutively. It is estimated that over 10% of the human genome consists of tandemly repeated sequences. Finding repeated regions in long sequences is important in sequence analysis.
Xiaowen Liu, Lusheng Wang 0001
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Biochemistry and Biophysics Reports, 2019 MUC5AC is a well-known gastric differentiation marker, which has been frequently used for the classification of stomach cancer. However, the molecular mechanism of regulation of MUC5AC expression remains to be elucidated.
Natsuko Kageyama-Yahara +6 more
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Identification of tandem repeat families from long-read sequences of Humulus lupulus.
PLoS ONE, 2020 Hop (Humulus lupulus L.) is known for its use as a bittering agent in beer and has a rich history of cultivation, beginning in Europe and now spanning the globe.
Katherine A Easterling +7 more
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