Results 1 to 10 of about 135,238 (262)
Efficient Synthesis of the Lewis A Tandem Repeat [PDF]
Molecules, 2016 The convergent synthesis of the Lewis A (Lea) tandem repeat is described. The Lea tandem repeat is a carbohydrate ligand for a mannose binding protein that shows potent inhibitory activity against carcinoma growth.
Akiharu Ueki, Akihiro Imamura
exaly +5 more sources
A comprehensive tandem repeat catalog of the human genome [PDF]
Nature CommunicationsWith the increasing availability of long-read sequencing data, high-quality human genome assemblies, and software for fully characterizing tandem repeats, genome-wide genotyping of tandem repeat loci on a population scale is becoming more feasible.
Readman Chiu +3 more
doaj +2 more sources
Short Tandem Repeat-Enriched Architectural RNAs in Nuclear Bodies: Functions and Associated Diseases
Non-coding RNA, 2020 Nuclear bodies are membraneless, phase-separated compartments that concentrate specific proteins and RNAs in the nucleus. They are believed to serve as sites for the modification, sequestration, and storage of specific factors, and to act as ...
Kensuke Ninomiya +2 more
exaly +3 more sources
TRsv: simultaneous detection of tandem repeat variations, structural variations, and short indels using long read sequencing data [PDF]
Genome BiologyTandem repeat copy number variations (TR-CNVs), structural variations (SVs), and short indels have been responsible for many diseases and traits, but no tools exist to distinguish and detect these variants.
Shunichi Kosugi, Chikashi Terao
doaj +2 more sources
Algorithmica, 2022 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Amihood Amir +4 more
openaire +3 more sources
Expanding the repertoire of human tandem repeat RNA-binding proteins.
PLoS ONE, 2023 Protein regions consisting of arrays of tandem repeats are known to bind other molecular partners, including nucleic acid molecules. Although the interactions between repeat proteins and DNA are already widely explored, studies characterising tandem ...
Agustín Ormazábal +6 more
doaj +1 more source
TRDB--The Tandem Repeats Database [PDF]
Nucleic Acids Research, 2007 Tandem repeats in DNA have been under intensive study for many years, first, as a consequence of their usefulness as genomic markers and DNA fingerprints and more recently as their role in human disease and regulatory processes has become apparent. The Tandem Repeats Database (TRDB) is a public repository of information on tandem repeats in genomic DNA.
Gelfand, Yevgeniy +2 more
openaire +3 more sources
BMC Medical Genomics, 2021 Background Tandem repeats are highly mutable and contribute to the development of human disease by a variety of mechanisms. It is difficult to predict which tandem repeats may cause a disease.
Satomi Mitsuhashi +2 more
doaj +1 more source
5meCpG epigenetic marks neighboring a primate-conserved core promoter short tandem repeat indicate X-chromosome inactivation. [PDF]
PLoS ONE, 2014 X-chromosome inactivation (XCI) is the epigenetic transcriptional silencing of an X-chromosome during the early stages of embryonic development in female eutherian mammals.
Filipe Brum Machado +12 more
doaj +1 more source
The MUC1 Cytoplasmic Tail and Tandem Repeat Domains Contribute to Mammary Oncogenesis in FVB Mice
Breast Cancer: Basic and Clinical Research, 2008 Background Though the importance of the transmembrane mucin MUC1 in mammary oncogenesis has long been recognized, the relative contributions of the cytoplasmic tail and tandem repeat domains are poorly understood. Methods To address this, mouse models of
Christine L. Hattrup +6 more
doaj +2 more sources