Results 11 to 20 of about 135,238 (262)

Global Repeat Map (GRM) Application: Finding All DNA Tandem Repeat Units

open access: yesAlgorithms, 2022
Tandem repeats (TRs) are important components of eukaryotic genomes; they have both structural and functional roles: (i) they form essential chromosome structures such as centromeres and telomeres; (ii) they modify chromatin structure and affect ...
Matko Glunčić   +3 more
doaj   +1 more source

Unique Features of Tandem Repeats in Bacteria [PDF]

open access: yesJournal of Bacteriology, 2020
We found an enigmatic group of noncoding satellites in 85 bacterial genomes with a constant repeat size but variable sequence. This pattern of DNA organization is unique and had not been previously described in bacteria. These findings strongly suggest that satellite size in some bacteria is under strong selective constraints and thus that satellites ...
Subirana Torrent, Juan A.   +1 more
openaire   +4 more sources

Digital genotyping of macrosatellites and multicopy genes reveals novel biological functions associated with copy number variation of large tandem repeats. [PDF]

open access: yesPLoS Genetics, 2014
Tandem repeats are common in eukaryotic genomes, but due to difficulties in assaying them remain poorly studied. Here, we demonstrate the utility of Nanostring technology as a targeted approach to perform accurate measurement of tandem repeats even at ...
Manisha Brahmachary   +6 more
doaj   +1 more source

Structural characteristics of a mitochondrial control region from Myotis bat (Vespertilionidae) mitogenomes based on sequence datasets

open access: yesData in Brief, 2019
The datasets included sequences of a control region from Myotis bat mitogenomes. The control region (1706–2005 bp) of the Myotis mitogenomes was divided into three domains similar to that of other mammals, which included the common conserved blocks (ETAS
Md M. Rahman   +2 more
doaj   +1 more source

Mapping the landscape of tandem repeat variability by targeted long read single molecule sequencing in familial X-linked intellectual disability

open access: yesBMC Medical Genomics, 2018
Background The etiology of more than half of all patients with X-linked intellectual disability remains elusive, despite array-based comparative genomic hybridization, whole exome or genome sequencing.
Alena Zablotskaya   +4 more
doaj   +1 more source

Microsatellite Stability in STR Analysis Aspergillus fumigatus Depends on Number of Repeat Units

open access: yesFrontiers in Cellular and Infection Microbiology, 2019
More than a decade ago a short tandem repeat-based typing method was developed for the fungus Aspergillus fumigatus. This STRAf assay is based on the analysis of nine short tandem repeat markers.
Theun de Groot   +3 more
doaj   +1 more source

Probabilistic approaches to alignment with tandem repeats [PDF]

open access: yesAlgorithms for Molecular Biology, 2013
Peer-reviewed and presented as part of the 13th Workshop on Algorithms in Bioinformatics (WABI2013)
Michal Nánási   +2 more
openaire   +4 more sources

LEPStr: A database for Mycobacterium leprae short tandem repeats

open access: yesInformatics in Medicine Unlocked, 2020
Short tandem repeats are short arrays of nucleotide sequences, and they have vital roles in many biological processes, including modulation of transcription, enhancement of gene expression, adaptation to a particular environment, and link to autosomal ...
Partha Sarathi Mohanty   +9 more
doaj   +1 more source

Counting short tandem repeats [PDF]

open access: yesNature Methods, 2020
A method using CRISPR–Cas technology, nanopore sequencing and bioinformatics enables quantification of short tandem repeats with high accuracy.
openaire   +2 more sources

TRAL: tandem repeat annotation library [PDF]

open access: yesBioinformatics, 2015
Abstract Motivation: Currently, more than 40 sequence tandem repeat detectors are published, providing heterogeneous, partly complementary, partly conflicting results. Results: We present TRAL, a tandem repeat annotation library that allows running and parsing of various detection outputs, clustering of redundant or ...
Elke Schaper   +8 more
openaire   +5 more sources

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