Results 11 to 20 of about 312,877 (298)

TRAL : tandem repeat annotation library [PDF]

Bioinformatics, 2015
Erworben im Rahmen der Schweizer Nationallizenzen (http://www.nationallizenzen.ch)Motivation: Currently, more than 40 sequence tandem repeat detectors are published, providing heterogeneous, partly complementary, partly conflicting results.
Anisimova, Maria, Korsunsky, Alexander, Messina, Antonio, Murri, Riccardo, Pečerska, Jūlija, Schaper, Elke, Stockinger, Heinz, Xenarios, Ioannis, Zoller, Stefan   +8 more
core   +7 more sources

A comprehensive tandem repeat catalog of the human genome [PDF]

Nature Communications
With the increasing availability of long-read sequencing data, high-quality human genome assemblies, and software for fully characterizing tandem repeats, genome-wide genotyping of tandem repeat loci on a population scale is becoming more feasible.
Readman Chiu, Indhu-Shree Rajan-Babu, Jan M. Friedman, Inanc Birol   +3 more
doaj   +2 more sources

Diversity in coding tandem repeats in related Neisseria spp. [PDF]

BMC Microbiology, 2003
Background Tandem repeats contained within coding regions can mediate phase variation when the repeated units change the reading frame of the coding sequence in a copy number dependent manner.
Saunders Nigel J, Snyder Lori AS, Jordan Philip   +2 more
doaj   +5 more sources

TRsv: simultaneous detection of tandem repeat variations, structural variations, and short indels using long read sequencing data [PDF]

Genome Biology
Tandem repeat copy number variations (TR-CNVs), structural variations (SVs), and short indels have been responsible for many diseases and traits, but no tools exist to distinguish and detect these variants.
Shunichi Kosugi, Chikashi Terao
doaj   +2 more sources

Analysis of the largest tandemly repeated DNA families in the human genome [PDF]

BMC Genomics, 2008
Background Tandemly Repeated DNA represents a large portion of the human genome, and accounts for a significant amount of copy number variation. Here we present a genome wide analysis of the largest tandem repeats found in the human genome sequence ...
Jin Xiaoping, Lescale Chloe, Guillem Flavia, Hasson Dan, Warburton Peter E, Abrusan Gyorgy   +5 more
doaj   +4 more sources

Expanding the repertoire of human tandem repeat RNA-binding proteins.

PLoS ONE, 2023
Protein regions consisting of arrays of tandem repeats are known to bind other molecular partners, including nucleic acid molecules. Although the interactions between repeat proteins and DNA are already widely explored, studies characterising tandem ...
Agustín Ormazábal, Matías Sebastián Carletti, Tadeo Enrique Saldaño, Martín Gonzalez Buitron, Julia Marchetti, Nicolas Palopoli, Alex Bateman   +6 more
doaj   +1 more source

Genome-wide survey of tandem repeats by nanopore sequencing shows that disease-associated repeats are more polymorphic in the general population

BMC Medical Genomics, 2021
Background Tandem repeats are highly mutable and contribute to the development of human disease by a variety of mechanisms. It is difficult to predict which tandem repeats may cause a disease.
Satomi Mitsuhashi, Martin C. Frith, Naomichi Matsumoto   +2 more
doaj   +1 more source

Double String Tandem Repeats

Algorithmica, 2022
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Amihood Amir, Ayelet Butman, Gad M. Landau, Shoshana Marcus, Dina Sokol   +4 more
openaire   +3 more sources

5meCpG epigenetic marks neighboring a primate-conserved core promoter short tandem repeat indicate X-chromosome inactivation. [PDF]

PLoS ONE, 2014
X-chromosome inactivation (XCI) is the epigenetic transcriptional silencing of an X-chromosome during the early stages of embryonic development in female eutherian mammals.
Filipe Brum Machado, Fabricio Brum Machado, Milena Amendro Faria, Viviane Lamim Lovatel, Antonio Francisco Alves da Silva, Claudia Pamela Radic, Carlos Daniel De Brasi, Álvaro Fabricio Lopes Rios, Susana Marina Chuva de Sousa Lopes, Leonardo Serafim da Silveira, Carlos Ramon Ruiz-Miranda, Ester Silveira Ramos, Enrique Medina-Acosta   +12 more
doaj   +1 more source

The MUC1 Cytoplasmic Tail and Tandem Repeat Domains Contribute to Mammary Oncogenesis in FVB Mice

Breast Cancer: Basic and Clinical Research, 2008
Background Though the importance of the transmembrane mucin MUC1 in mammary oncogenesis has long been recognized, the relative contributions of the cytoplasmic tail and tandem repeat domains are poorly understood. Methods To address this, mouse models of
Christine L. Hattrup, Judy M. Bradley, Kari L. Kotlarczyk, Cathy S. Madsen, Joseph G. Hentz, Ronald J. Marler, Sandra J. Gendler   +6 more
doaj   +2 more sources