Results 1 to 10 of about 90,397 (258)

Short Tandem Repeat-Enriched Architectural RNAs in Nuclear Bodies: Functions and Associated Diseases

Non-Coding RNA, 2020
Nuclear bodies are membraneless, phase-separated compartments that concentrate specific proteins and RNAs in the nucleus. They are believed to serve as sites for the modification, sequestration, and storage of specific factors, and to act as ...
Kensuke Ninomiya, Tetsuro Hirose
doaj   +3 more sources

Recombinase polymerase amplification of forensic short tandem repeat loci [PDF]

Scientific Reports
Short tandem repeats (STRs) are highly polymorphic repetitive DNA sequences extensively used in forensic science for identification of individuals. STR genotyping is usually performed by capillary electrophoresis (CE) or next-generation sequencing (NGS ...
Sonja Škevin, Liesl De Keyzer, Lynn De Waele, Olivier Tytgat, David Van Hoofstat, Dieter Deforce, Filip Van Nieuwerburgh   +6 more
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Short tandem repeat expansions in patients with neurodegenerative dementiaResearch in context [PDF]

EBioMedicine
Summary: Background: Due to the overlapping clinical features of neurodegenerative dementia (NDD)—including Alzheimer's disease (AD), frontotemporal dementia (FTD), dementia with Lewy bodies (DLB), and progressive supranuclear palsy (PSP), accurate ...
Yuan Zhu, Xuewen Xiao, Yiliang Liu, Zheng Wang, Tengfei Luo, Tianyan Xu, Qijie Yang, Xiaoli Hao, Cong Zhang, Sizhe Zhang, Shilin Luo, Yafang Zhou, Xinxin Liao, Yun Tian, Ling Weng, Liangjuan Fang, Beisha Tang, Bin Jiao, Jinchen Li, Lu Shen   +19 more
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Uterine teratoma and the role of short-tandem repeat genotyping in understanding origins [PDF]

Gynecologic Oncology Reports
Background: Uterine teratomas are a rare entity with a debated origin. Given its rarity and limitations of diagnostic imaging, diagnosis is typically determined pathologically following surgical resection based on the presence of tissue derived from all ...
Abdelrahman AlAshqar, Vijaya Kadam Maruthi, Rita Abi-Raad, Michelle Greenman, Pei Hui, Elena Ratner, Gary Altwerger, Alessandro Santin, Vaagn Andikyan   +8 more
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Diverse short tandem repeat sequences influence gene regulation in human populations [PDF]

Genome Biology
Background Short tandem repeat (STR) length is a known determinant of pathogenicity in a variety of human disorders. The repeat sequence itself can modulate disease severity and penetrance; however, the broader impact of STR sequence variation on gene ...
Aleksandra Mitina, Worrawat Engchuan, Brett Trost, Giovanna Pellecchia, Stephen W. Scherer, Ryan K. C. Yuen   +5 more
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Short tandem repeat mutations regulate gene expression in colorectal cancer [PDF]

Scientific Reports
Short tandem repeat (STR) mutations are prevalent in colorectal cancer (CRC), especially in tumours with the microsatellite instability (MSI) phenotype. While STR length variations are known to regulate gene expression under physiological conditions, the
Max A. Verbiest, Oxana Lundström, Feifei Xia, Michael Baudis, Tugce Bilgin Sonay, Maria Anisimova   +5 more
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Short tandem repeat profiling via next-generation sequencing for cell line authentication [PDF]

Disease Models & Mechanisms, 2023
Yi-Hsien Chen, Jon P. Connelly, Colin Florian, Xiaoxia Cui, Shondra M. Pruett-Miller   +4 more
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Linked-read sequencing for detecting short tandem repeat expansions

Scientific Reports, 2022
Detection of short tandem repeat (STR) expansions with standard short-read sequencing is challenging due to the difficulty in mapping multicopy repeat sequences.
Readman Chiu, Indhu-Shree Rajan-Babu, Inanc Birol, Jan M. Friedman   +3 more
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LEPStr: A database for Mycobacterium leprae short tandem repeats

Informatics in Medicine Unlocked, 2020
Short tandem repeats are short arrays of nucleotide sequences, and they have vital roles in many biological processes, including modulation of transcription, enhancement of gene expression, adaptation to a particular environment, and link to autosomal ...
Partha Sarathi Mohanty, Dimple Saikia, Siddhant Kalra, Farah Naaz, Avi Kumar Bansal, Harpreet Singh Pawar, Keshar Kunja Mohanty, Sandeep Sharma, Manjula Singh, Shripad A. Patil   +9 more
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Optimization and Validation of Candida auris Short Tandem Repeat Analysis

Microbiology Spectrum, 2022
Candida auris is an easily transmissible yeast with resistance to different antifungal compounds. Outbreaks of C. auris are mostly observed in intensive care units.
Theun de Groot, Bram Spruijtenburg, Lindsay A. Parnell, Nancy A. Chow, Jacques F. Meis   +4 more
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