Results 1 to 10 of about 1,087 (116)
Short Tandem Repeat-Enriched Architectural RNAs in Nuclear Bodies: Functions and Associated Diseases
Non-Coding RNA, 2020 Nuclear bodies are membraneless, phase-separated compartments that concentrate specific proteins and RNAs in the nucleus. They are believed to serve as sites for the modification, sequestration, and storage of specific factors, and to act as ...
Kensuke Ninomiya, Tetsuro Hirose
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Native functions of short tandem repeats
eLife, 2023 Over a third of the human genome is comprised of repetitive sequences, including more than a million short tandem repeats (STRs). While studies of the pathologic consequences of repeat expansions that cause syndromic human diseases are extensive, the potential native functions of STRs are often ignored.
Shannon E Wright, Peter K Todd
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Linked-read sequencing for detecting short tandem repeat expansions
Scientific Reports, 2022 Detection of short tandem repeat (STR) expansions with standard short-read sequencing is challenging due to the difficulty in mapping multicopy repeat sequences.
Readman Chiu +3 more
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Counting short tandem repeats [PDF]
Nature Methods, 2020 A method using CRISPR–Cas technology, nanopore sequencing and bioinformatics enables quantification of short tandem repeats with high accuracy.
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LEPStr: A database for Mycobacterium leprae short tandem repeats
Informatics in Medicine Unlocked, 2020 Short tandem repeats are short arrays of nucleotide sequences, and they have vital roles in many biological processes, including modulation of transcription, enhancement of gene expression, adaptation to a particular environment, and link to autosomal ...
Partha Sarathi Mohanty +9 more
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Mutation of human short tandem repeats [PDF]
Human Molecular Genetics, 1993 A total of 20,000 parent-offspring transfers of alleles were examined through the genotyping within 40 CEPH reference families of 28 short tandem repeat polymorphisms (STRPs) located on chromosome 19. Forty-seven initial mutation events were detected in the STRPs using DNA from transformed lymphoblastoid cell lines, but less than half (39%) could be ...
J L, Weber, C, Wong
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Optimization and Validation of Candida auris Short Tandem Repeat Analysis
Microbiology Spectrum, 2022 Candida auris is an easily transmissible yeast with resistance to different antifungal compounds. Outbreaks of C. auris are mostly observed in intensive care units.
Theun de Groot +4 more
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DeepRepeat: direct quantification of short tandem repeats on signal data from nanopore sequencing
Genome Biology, 2022 Despite recent improvements in basecalling accuracy, nanopore sequencing still has higher error rates on short-tandem repeats (STRs). Instead of using basecalled reads, we developed DeepRepeat which converts ionic current signals into red-green-blue ...
Li Fang +5 more
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Data in Brief, 2019 The datasets included sequences of a control region from Myotis bat mitogenomes. The control region (1706–2005 bp) of the Myotis mitogenomes was divided into three domains similar to that of other mammals, which included the common conserved blocks (ETAS
Md M. Rahman +2 more
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Microsatellite Stability in STR Analysis Aspergillus fumigatus Depends on Number of Repeat Units
Frontiers in Cellular and Infection Microbiology, 2019 More than a decade ago a short tandem repeat-based typing method was developed for the fungus Aspergillus fumigatus. This STRAf assay is based on the analysis of nine short tandem repeat markers.
Theun de Groot +3 more
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