Results 21 to 30 of about 90,397 (258)

A Brief Review of Short Tandem Repeat Mutation

Genomics, Proteomics & Bioinformatics, 2007
Abstract Short tandem repeats (STRs) are short tandemly repeated DNA sequences that involve a repetitive unit of 1–6 bp. Because of their polymorphisms and high mutation rates, STRs are widely used in biological research. Strand-slippage replication is the predominant mutation mechanism of STRs, and the stepwise mutation model is ...
Hao Fan, Jia-You Chu
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Comparison of the Frequency of Y-short Tandem Repeats Markers between Sadat and Non-Sadat Populations in Isfahan Province of Iran

Advanced Biomedical Research, 2017
Background: Y chromosome is one of the two sex chromosomes and is male specific. Due to limited genetic exchange, the main part of that is passed virtually unchanged from one generation to next generation.
Reihaneh Seyedebrahimi, Ebrahim Esfandiari, Bahman Rashidi, Rasoul Salehi, Ali Gholami Dahghi, Shahriar Dabiri, Majid Kheirollahi   +6 more
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Quantification of mixed chimerism allows early therapeutic interventions

Revista Brasileira de Hematologia e Hemoterapia, 2014
Hematopoietic stem cell transplantation is the curative option for patients with myelodysplastic syndrome; however, it requires a long post-transplantation follow-up.
Jóice Merzoni, Gisele Menezes Ewald, Alessandra Aparecida Paz, Liane Esteves Daudt, Luiz Fernando Job Jobim   +4 more
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Using short tandem repeat profiling to validate cell lines in biobanks

Кардиоваскулярная терапия и профилактика, 2022
Aim. To approve the COrDIS kit (Gordiz, Russia) for the authenticity of cell lines from the Bioresource Collection of the N.N. Blokhin National Medical Research Center of Oncology by the short tandem repeat (STR) profiling.Material and methods.
E. N. Kosobokova, A. A. Malchenkova, N. A. Kalinina, V. S. Kosorukov   +3 more
doaj   +1 more source

Short tandem repeat polymorphism evolution in humans [PDF]

European Journal of Human Genetics, 1998
Forty-five dinucleotide short tandem repeat polymorphisms were typed in ten large samples of a globally distributed set of populations. Although these markers had been selected for high heterozygosity in European populations, we found them to be sufficiently informative for linkage analysis in non-Europeans.
F, Calafell, A, Shuster, W C, Speed, J R, Kidd, K K, Kidd   +4 more
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Reuse of Denaturing Polyacrylamide Gels for Short Tandem Repeat Analysis

BioTechniques, 1998
Denaturing polyacrylamide gel electrophoretic analysis of amplified polymorphic short tandem repeat (STR) loci using fluorescent markers is a mainstay of forensic and paternity testing.
Allan Tereba, Katherine A. Micka, James W. Schumm   +2 more
doaj   +1 more source

An update on the neurological short tandem repeat expansion disorders and the emergence of long-read sequencing diagnostics

Acta Neuropathologica Communications, 2021
Background Short tandem repeat (STR) expansion disorders are an important cause of human neurological disease. They have an established role in more than 40 different phenotypes including the myotonic dystrophies, Fragile X syndrome, Huntington’s disease,
Sanjog R. Chintalaphani, Sandy S. Pineda, Ira W. Deveson, Kishore R. Kumar   +3 more
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Forensic identification of missing persons using DNA from surviving relatives and femur bone retrieved from salty environment

Journal of Forensic Science and Medicine, 2020
Human identification using forensic DNA profiling has made enormous advancement over the past two-and-half decades. Forensic DNA profiling provides enormous genetic data from a variety of biological materials and individuals to help solve many important ...
Kofi Adjapong Afrifah, Alexander Badu-Boateng, Samuel Antwi-Akomeah, Eva Emefa Motey, Emmanuel Boampong, Peter Twumasi, Paul Poku Sampene, Augustine Donkor   +7 more
doaj   +1 more source

Short-tandem repeat analysis in seven Chinese regional populations

Genetics and Molecular Biology, 2010
In the present study, we investigated the application of 13 short tandem repeat (STR) loci (D13S317, D7S820, TH01, D16S539, CSFIPO, VWA, D8S1179, TPOX, FGA, D3S1358, D21S11, D18S51 and D5S818) routinely used in forensic analysis, for delineating ...
Xing-bo Song, Yi Zhou, Bin-wu Ying, Lan-lan Wang, Yi-song Li, Jian-feng Liu, Xiao-gang Bai, Lei Zhang, Xiao-jun Lu, Jun Wang, Yuan-xin Ye   +10 more
doaj   +1 more source

lobSTR: A Short Tandem Repeat Profiler for Personal Genomes [PDF]

Genome Research, 2012
Short tandem repeats (STRs) have a wide range of applications, including medical genetics, forensics, and genetic genealogy. High-throughput sequencing (HTS) has the potential to profile hundreds of thousands of STR loci. However, mainstream bioinformatics pipelines are inadequate for the task.
Melissa Gymrek, David Golan, Saharon Rosset, Yaniv Erlich   +3 more
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