Results 41 to 50 of about 3,711,281 (293)

A fast and effective approach for the detection of units in tandem repeat proteins [PDF]

, 2022
openA fast and effective approach for the detection of units in tandem repeat proteinsA fast and effective approach for the detection of units in tandem repeat ...
COCCO, ALBERTO
core  

Short-tandem repeat analysis in seven Chinese regional populations

Genetics and Molecular Biology, 2010
In the present study, we investigated the application of 13 short tandem repeat (STR) loci (D13S317, D7S820, TH01, D16S539, CSFIPO, VWA, D8S1179, TPOX, FGA, D3S1358, D21S11, D18S51 and D5S818) routinely used in forensic analysis, for delineating ...
Xing-bo Song, Yi Zhou, Bin-wu Ying, Lan-lan Wang, Yi-song Li, Jian-feng Liu, Xiao-gang Bai, Lei Zhang, Xiao-jun Lu, Jun Wang, Yuan-xin Ye   +10 more
doaj   +1 more source

Genetic analysis of DXS101and DXS6807 short tandem repeat (X-STR) in samples of Iraqi Arab male population

مجلة مركز بحوث التقنيات الاحيائية, 2020
Back ground: X-chromosomal short tandem repeats (X-STRs) have assured to be informative and particular role in complex relationship testing. DXS6807 known as tetra nucleotides polymorphism representing eight alleles of 251-275 bp in length.
Hayder Allawi Khaleefah , Salwa Jaber Abdullah Al-Awadi, Zaid Nsaif Abbas Al-Tameemi   +2 more
doaj   +1 more source

Comprehensive DNA profiling strategy for patient-derived xenograft model authentication in the J-PDX library

Scientific Reports
Patient-derived xenograft models are crucial in cancer research, although authentication methods remain limited. This study developed a comprehensive DNA profiling strategy for patient-derived xenograft quality control in the J-PDX Library by comparing ...
Tomomi Yoshino, Shigehiro Yagishita, Mami Takahashi, Chiaki Ushie, Ako Takahashi, Yasushi Yatabe, Shinji Kohsaka, Toshihide Ueno, Hanako Ono, Kouya Shiraishi, Akinobu Hamada   +10 more
doaj   +1 more source

General Approach to Analysis of Polymorphic Short Tandem Repeat Loci

BioTechniques, 1996
Polymerase chain reaction amplification products of 22 known polymorphic short tandem repeat (STR) loci were subjected to denaturing polyacrylamide gel electrophoresis and detected using a silver staining method.
Cynthia J. Sprecher, Christoph Puers, Ann M. Lins, James W. Schumm   +3 more
doaj   +1 more source

The effect of temperature and storage time of cuccal swabs on FGA and D13S317 loci with the STR PCR method

Jurnal Teknologi Laboratorium, 2020
The samples used for forensic DNA analysis in living individuals are usually blood and buccal swabs, however, blood collection requires an invasive method that can cause discomfort, thus a buccal swab can be a good choice for individuals examined ...
Indah Nuraini Masjkur, Evy Arfianti, Ahmad Yudianto, Abdul Hadi Furqoni, Qurrota A’yun   +4 more
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Classification and Automatic Annotation of Tandem Repeat Proteins in RepeatsDB [PDF]

, 2023
openProtein tandem repeats are crucial structural elements in various biological processes, playing essential roles in cell adhesion, protein-protein interactions, and molecular recognition.
MOZAFFARI, SOROUSH
core  

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source