Results 21 to 30 of about 135,238 (262)
Genome Biology, 2019 Technological limitations have hindered the large-scale genetic investigation of tandem repeats in disease. We show that long-read sequencing with a single Oxford Nanopore Technologies PromethION flow cell per individual achieves 30× human genome ...
Arne De Roeck +10 more
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TROLL—Tandem Repeat Occurrence Locator [PDF]
Bioinformatics, 2002 Abstract Summary: Tandem Repeat Occurrence Locator (TROLL), is a light-weight Simple Sequence Repeat (SSR) finder based on a slight modification of the Aho–Corasick algorithm. It is fast and only requires a standard Personal Computer (PC) to operate.
Adalberto T. Castelo +2 more
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Rediscovering tandem repeat variation in schizophrenia: challenges and opportunities
Translational Psychiatry, 2023 Tandem repeats (TRs) are prevalent throughout the genome, constituting at least 3% of the genome, and often highly polymorphic. The high mutation rate of TRs, which can be orders of magnitude higher than single-nucleotide polymorphisms and indels ...
Rebecca Birnbaum
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Biochemistry and Biophysics Reports, 2019 MUC5AC is a well-known gastric differentiation marker, which has been frequently used for the classification of stomach cancer. However, the molecular mechanism of regulation of MUC5AC expression remains to be elucidated.
Natsuko Kageyama-Yahara +6 more
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Food Chemistry: Molecular Sciences, 2023 The 13S globulin zero-repeat subunit is resistant to trypsin and may have higher allergenicity than the 1–6 tandem repeat subunits in common buckwheat (Fagopyrum esculentum Moench).
Takeyuki Okada +3 more
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Genetic Diversity and Genotype Distribution of Erwinia amylovora in Korea [PDF]
The Plant Pathology JournalErwinia amylovora, first identified in 1793 in Hudson Valley (New York, USA), has a genome size of 3.7–4.0 Mb. E. amylovora bacterial strains are classified based on the infecting hosts: the Amygdaloideae-infecting (AI) group, targeting apple and pear ...
Hyeonheui Ham +2 more
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Biomedicines, 2023 Short tandem repeats (STRs) are units of 1–6 base pairs that occur in tandem repetition to form a repeat tract. STRs exhibit repeat instability, which generates expansions or contractions of the repeat tract.
Stephanie Calluori +2 more
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Evolution and control of imprinted FWA genes in the genus Arabidopsis. [PDF]
PLoS Genetics, 2008 A central question in genomic imprinting is how a specific sequence is recognized as the target for epigenetic marking. In both mammals and plants, imprinted genes are often associated with tandem repeats and transposon-related sequences, but the role of
Ryo Fujimoto +9 more
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RNA biology of disease-associated microsatellite repeat expansions
Acta Neuropathologica Communications, 2017 Microsatellites, or simple tandem repeat sequences, occur naturally in the human genome and have important roles in genome evolution and function. However, the expansion of microsatellites is associated with over two dozen neurological diseases. A common
Kushal J. Rohilla, Keith T. Gagnon
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A tandem repeat gene in a picornavirus
Nucleic Acids Research, 1982 Three closely related genes for the small genome-linked protein (VPg) of picornaviruses have been identified by sequence analysis as a tandem repeat in the genome of Foot and Mouth Disease Virus (FMDV), strain O1K. This unusual structure was also found in the genome of strain C1O, belonging to a different FMDV serotype. Predicted biochemical properties
S, Forss, H, Schaller
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