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Global Repeat Map (GRM) Application: Finding All DNA Tandem Repeat Units
Algorithms, 2022 Tandem repeats (TRs) are important components of eukaryotic genomes; they have both structural and functional roles: (i) they form essential chromosome structures such as centromeres and telomeres; (ii) they modify chromatin structure and affect ...
Matko Glunčić +3 more
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Digital genotyping of macrosatellites and multicopy genes reveals novel biological functions associated with copy number variation of large tandem repeats. [PDF]
PLoS Genetics, 2014 Tandem repeats are common in eukaryotic genomes, but due to difficulties in assaying them remain poorly studied. Here, we demonstrate the utility of Nanostring technology as a targeted approach to perform accurate measurement of tandem repeats even at ...
Manisha Brahmachary +6 more
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TRDB--The Tandem Repeats Database [PDF]
Nucleic Acids Research, 2007 Tandem repeats in DNA have been under intensive study for many years, first, as a consequence of their usefulness as genomic markers and DNA fingerprints and more recently as their role in human disease and regulatory processes has become apparent. The Tandem Repeats Database (TRDB) is a public repository of information on tandem repeats in genomic DNA.
Gelfand, Yevgeniy +2 more
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Data in Brief, 2019 The datasets included sequences of a control region from Myotis bat mitogenomes. The control region (1706–2005 bp) of the Myotis mitogenomes was divided into three domains similar to that of other mammals, which included the common conserved blocks (ETAS
Md M. Rahman +2 more
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Comparative Analysis of Tandem Repeats from Hundreds of Species Reveals Unique Insights into Centromere Evolution [PDF]
, 2012 Centromeres are essential for chromosome segregation, yet their DNA sequences evolve rapidly. In most animals and plants that have been studied, centromeres contain megabase-scale arrays of tandem repeats.
Bradnam, Keith R. +16 more
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BMC Medical Genomics, 2018 Background The etiology of more than half of all patients with X-linked intellectual disability remains elusive, despite array-based comparative genomic hybridization, whole exome or genome sequencing.
Alena Zablotskaya +4 more
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Ligand selectivity in stabilising tandem parallel folded G-quadruplex motifs in human telomeric DNA sequences [PDF]
, 2014 Biophysical studies of ligand interactions with three human telomeric repeat sequences (d(AGGG(TTAGGG)n, n = 3, 7 and 11)) show that an oxazole-based ‘click’ ligand, which induces parallel folded quadruplexes, preferentially stabilises longer telomeric ...
Alex R. O. Cousins +38 more
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Counting short tandem repeats [PDF]
Nature Methods, 2020 A method using CRISPR–Cas technology, nanopore sequencing and bioinformatics enables quantification of short tandem repeats with high accuracy.
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Microsatellite Stability in STR Analysis Aspergillus fumigatus Depends on Number of Repeat Units
Frontiers in Cellular and Infection Microbiology, 2019 More than a decade ago a short tandem repeat-based typing method was developed for the fungus Aspergillus fumigatus. This STRAf assay is based on the analysis of nine short tandem repeat markers.
Theun de Groot +3 more
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Short Tandem Repeat-Enriched Architectural RNAs in Nuclear Bodies: Functions and Associated Diseases
Non-Coding RNA, 2020 Nuclear bodies are membraneless, phase-separated compartments that concentrate specific proteins and RNAs in the nucleus. They are believed to serve as sites for the modification, sequestration, and storage of specific factors, and to act as ...
Kensuke Ninomiya, Tetsuro Hirose
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