Results 21 to 30 of about 177,651 (293)

Genome-wide survey of tandem repeats by nanopore sequencing shows that disease-associated repeats are more polymorphic in the general population

BMC Medical Genomics, 2021
Background Tandem repeats are highly mutable and contribute to the development of human disease by a variety of mechanisms. It is difficult to predict which tandem repeats may cause a disease.
Satomi Mitsuhashi, Martin C. Frith, Naomichi Matsumoto   +2 more
doaj   +1 more source

Molecular cytogenetic mapping of Cucumis sativus and C. melo using highly repetitive DNA sequences [PDF]

, 2010
Chromosomes often serve as one of the most important molecular aspects of studying the evolution of species. Indeed, most of the crucial mutations that led to differentiation of species during the evolution have occurred at the chromosomal level ...
Bang, J.W., Choi, D., Hur, Y., Jong, J.H.S.G.M., de, Koo, D.H., Nam, Y.W.   +5 more
core   +6 more sources

Chromosomal-level assembly of the Asian Seabass genome using long sequence reads and multi-layered scaffolding [PDF]

, 2016
We report here the ~670 Mb genome assembly of the Asian seabass (Lates calcarifer), a tropical marine teleost. We used long-read sequencing augmented by transcriptomics, optical and genetic mapping along with shared synteny from closely related fish ...
A Bairoch, A Christoffels, A Gurevich, A Kozomara, A McKenna, A Mitchell, A Morgulis, A Morgulis, A Pradhan, A Reiner, A Rodriguez-Mari, A Stamatakis, A Yates, AI Makunin, AJ Enright, AL Price, AL Price, Alan Christoffels, Aleksey Komissarov, Alexey Tupikin, Amy Hin Yan Tong, Andrey A. Yurchenko, AR Quinlan, B Langmead, B Star, C Berthelot, C Camacho, C Holt, C Wang, Chen-Shan Chin, CS Chin, D Brawand, D Ellinghaus, DA Benson, Darrell Green, DC Hardie, Dean R. Jerry, DH Alexander, Doreen Lau, DR Kelley, DRS-K, C. Jerry, E Casacuberta, E. TG Staristina, EW Myers, F Abascal, F Chen, F Yang, FC Jones, FJ Krsticevic, Fritz J. Sedlazeck, G Abrusan, G Benson, G Lin, G Marcais, G Parra, G Parra, G Tamazian, GH Yue, GH Yue, Gopikrishna Gopalapillai, Gregory W. Vurture, GS Slater, GT Valente, H Li, H Saiga, Heiner Kuhl, HH Kazazian Jr., I Braasch, Inna S. Kuznetsova, IS Kuznetsova, J Castresana, J Eid, J Huerta-Cepas, J Jurka, J Lin, James P. Drake, JG Ruby, JN Volff, JN Volff, Jolly M. Saju, Jonas Korlach, JS Chew, Junhui Jiang, K Howe, K Katoh, K Prufer, Kathiresan Purushothaman, KD Pruitt, KJ Hoff, KP Koepfli, KW Tzung, Lawrence S. Hon, László Orbán, M Blanchette, M Kanehisa, M Kasahara, M Kolmogorov, M Krzywinski, M Martin, M Schartl, M Tarailoâ-Graovac, M Tine, MA Larkin, Mario Jonas, Marsel Kabilov, Matthew Boitano, MB Stocks, MG Grabherr, Michael C. Schatz, MJ Chaisson, MR Friedlander, N Siegel, Natascha M. Thevasagayam, NM Thevasagayam, O Jaillon, O Otero, P Cingolani, P Ravi, P Schattner, P Shannon, P Xu, Paul M. Richardson, PE Warburton, Peter Van Heusden, R Kajitani, R Lorenz, R Luo, R Moore, R Pethiyagoda, R Poulter, R She, R Sreenivasan, Ramkumar Lachumanan, RD Ward, RD Ward, Richard Hall, RJ Roberts, S Chen, S Guindon, S Hoegg, S Hoegg, S Koren, S Vij, S Zhou, Sai Rama Sridatta Prakki, Sarah Mwangi, SF Altschul, Shubha Vij, Si Lok, Si Yan Ngoh, Siddharth Singh, Simon Moxon, SM Kielbasa, Sridhar Sivasubbu, Stanley Kimbung Mbandi, Stephen J. O'Brien, Stephen W. Turner, T Anantharaman, Tamás Dalmay, Tansyn H. Noble, TD Wu, TF DeLuca, TH O'Hare, TLO Davis, TS Anantharaman, Tyler Garvin, U Consortium, U Grimholt, V Douard, V Ravi, Vinaya Kumar Katneni, Vinod Scaria, Vladimir Trifonov, W Xue, WC Liew, Woei Chang Liew, WS Davidson, X Huang, X Zheng, XG Wang, XG Wang, Xueyan Shen, Y Guiguen, Y Han, Y Hashiguchi, Y Moriya, Y Sato, Y Sato, Y Sato, Z Lai, Ø Hammer   +190 more
core   +10 more sources

Structural characteristics of a mitochondrial control region from Myotis bat (Vespertilionidae) mitogenomes based on sequence datasets

Data in Brief, 2019
The datasets included sequences of a control region from Myotis bat mitogenomes. The control region (1706–2005 bp) of the Myotis mitogenomes was divided into three domains similar to that of other mammals, which included the common conserved blocks (ETAS
Md M. Rahman, Kwang B. Yoon, Yung C. Park   +2 more
doaj   +1 more source

Reconstructing the history of a WD40 beta-propeller tandem repeat using a phylogenetically informed algorithm [PDF]

PeerJ Computer Science, 2015
Tandem repeat sequences have been found in great numbers in proteins that are conserved in a wide range of living species. In order to reconstruct the evolutionary history of such sequences, it is necessary to develop algorithms and methods that can work
Philippe Lavoie-Mongrain, Mahdi Belcaid, Aïda Ouangraoua, Anne Bergeron, Guylaine Poisson   +4 more
doaj   +2 more sources

Ligand selectivity in stabilising tandem parallel folded G-quadruplex motifs in human telomeric DNA sequences [PDF]

, 2014
Biophysical studies of ligand interactions with three human telomeric repeat sequences (d(AGGG(TTAGGG)n, n = 3, 7 and 11)) show that an oxazole-based ‘click’ ligand, which induces parallel folded quadruplexes, preferentially stabilises longer telomeric ...
Alex R. O. Cousins, Balkwill, Bejugam, Biffi, Brooks, De Armond, De Cian, Dougal Ritson, Feng, Fernando, Fletcher, Garner, Grand, Haider, Huppert, John E. Moses, Kim, Kumari, Lingner, Lipps, Malcolm F. G. Stevens, Mark S. Searle, Mergny, Moorhouse, Moorhouse, Nakamura, Neidle, Pallavi Sharma, Petraccone, Petraccone, Randall, Renciuk, Ritson, Searle, Siddiqui-Jain, Todd, Vorlickova, Wang, Xu   +38 more
core   +1 more source

TRAL : tandem repeat annotation library [PDF]

, 2015
Erworben im Rahmen der Schweizer Nationallizenzen (http://www.nationallizenzen.ch)Motivation: Currently, more than 40 sequence tandem repeat detectors are published, providing heterogeneous, partly complementary, partly conflicting results.
Anisimova, Maria, Korsunsky, Alexander, Messina, Antonio, Murri, Riccardo, Pečerska, Jūlija, Schaper, Elke, Stockinger, Heinz, Xenarios, Ioannis, Zoller, Stefan   +8 more
core   +1 more source

Comparative Analysis of Tandem Repeats from Hundreds of Species Reveals Unique Insights into Centromere Evolution [PDF]

, 2012
Centromeres are essential for chromosome segregation, yet their DNA sequences evolve rapidly. In most animals and plants that have been studied, centromeres contain megabase-scale arrays of tandem repeats.
Bradnam, Keith R., Chan, Simon W. -L., DeRisi, Joseph L., Eid, John, Garcia, José Fernando, Korf, Ian F., May, Michael R., Melters, Daniël P., Peluso, Paul, Rank, David, Ross-Ibarra, Jeffrey, Ruby, J. Graham, Sebra, Robert, Smith, Timothy, Telis, Natalie, Tobias, Christian, Young, Hugh A.   +16 more
core   +4 more sources

Estimation of duplication history under a stochastic model for tandem repeats

BMC Bioinformatics, 2019
Background Tandem repeat sequences are common in the genomes of many organisms and are known to cause important phenomena such as gene silencing and rapid morphological changes. Due to the presence of multiple copies of the same pattern in tandem repeats
Farzad Farnoud, Moshe Schwartz, Jehoshua Bruck   +2 more
doaj   +1 more source

Specific tandem repeats are sufficient for paramutation-induced trans-generational silencing. [PDF]

PLoS Genetics, 2013
Paramutation is a well-studied epigenetic phenomenon in which trans communication between two different alleles leads to meiotically heritable transcriptional silencing of one of the alleles.
Christiane L Belele, Lyudmila Sidorenko, Maike Stam, Rechien Bader, Mario A Arteaga-Vazquez, Vicki L Chandler   +5 more
doaj   +1 more source