Results 51 to 60 of about 253,337 (321)

Identification and Monitoring of Nucleotide Repeat Expansions Using Southern Blotting in Drosophila Models of C9orf72 Motor Neuron Disease and Frontotemporal Dementia

Bio-Protocol, 2022
Repeat expansion diseases, including fragile X syndrome, Huntington’s disease, and C9orf72-related motor neuron disease and frontotemporal dementia, are a group of disorders associated with polymorphic expansions of tandem repeat nucleotide sequences ...
Joanne Sharpe, Nikki Harper, Ryan West
doaj   +1 more source

Tandem repeat copy-number variation in protein-coding regions of human genes

, 2005
BACKGROUND: Tandem repeat variation in protein-coding regions will alter protein length and may introduce frameshifts. Tandem repeat variants are associated with variation in pathogenicity in bacteria and with human disease.
O'Dushlaine, Colm T., Edwards, Richard, Park, Stephen D., Richard J Edwards, Colm T O'Dushlaine, Denis C Shields, Shields, Denis C., Stephen D Park   +7 more
core   +1 more source

ProRepeat: an integrated repository for studying amino acid tandem repeats in proteins

, 2011
ProRepeat (http://prorepeat.bioinformatics.nl/) is an integrated curated repository and analysis platform for in-depth research on the biological characteristics of amino acid tandem repeats.
Harm Nijveen, Lin, K., Jack A. M. Leunissen, K. Lin, Audrey David, Luo, H., Ke Lin, A. David, David, A., H. Nijveen, H. Luo, Leunissen, J.A.M., Nijveen, H., Hong Luo, J. A. M. Leunissen   +14 more
core   +1 more source

Sunflower centromeres consist of a centromere-specific LINE and a chromosome-specific tandem repeat

Frontiers in Plant Science, 2015
The kinetochore is a protein complex including kinetochore-specific proteins that plays a role in chromatid segregation during mitosis and meiosis. The complex associates with centromeric DNA sequences that are usually species-specific. In plant species,
Kiyotaka eNagaki, Keisuke eTanaka, Naoki eYamaji, Hisato eKobayashi, Minoru eMurata   +4 more
doaj   +1 more source

RIPCAL: a tool for alignment-based analysis of repeat-induced point mutations in fungal genomic sequences

, 2008
Background Repeat-induced point mutation (RIP) is a fungal-specific genome defence mechanism that alters the sequences of repetitive DNA, thereby inactivating coding genes.
Hane, J., Oliver, Richard, James K Hane, Richard P Oliver, Oliver, R.P., Hane James K, Hane, J.K., Oliver Richard P   +7 more
core   +1 more source

Evolution of Tandem Repeats Is Mirroring Post-polyploid Cladogenesis in Heliophila (Brassicaceae)

Frontiers in Plant Science, 2021
The unigeneric tribe Heliophileae encompassing more than 100 Heliophila species is morphologically the most diverse Brassicaceae lineage. The tribe is endemic to southern Africa, confined chiefly to the southwestern South Africa, home of two biodiversity
Mert Dogan, Mert Dogan, Milan Pouch, Milan Pouch, Terezie Mandáková, Terezie Mandáková, Petra Hloušková, Xinyi Guo, Pieter Winter, Zuzana Chumová, Adriaan Van Niekerk, Klaus Mummenhoff, Ihsan A. Al-Shehbaz, Ladislav Mucina, Ladislav Mucina, Martin A. Lysak, Martin A. Lysak   +16 more
doaj   +1 more source

Finding the region of pseudo-periodic tandem repeats in biological sequences [PDF]

Algorithms for Molecular Biology, 2006
The genomes of many species are dominated by short sequences repeated consecutively. It is estimated that over 10% of the human genome consists of tandemly repeated sequences. Finding repeated regions in long sequences is important in sequence analysis.
Xiaowen Liu, Lusheng Wang 0001
openaire   +3 more sources

Short tandem repeat sequences in the Mycoplasma genitalium genome and their use in a multilocus genotyping system

BMC Microbiology, 2008
BackgroundSeveral methods have been reported for strain typing of Mycoplasma genitalium. The value of these methods has never been comparatively assessed.
Liang Ma, Stephanie N. Taylor, J. Jensen, L. Myers, R. Lillis, D. Martin   +5 more
semanticscholar   +1 more source

Multiple locus VNTR analysis highlights that geographical clustering and distribution of Dichelobacter nodosus, the causal agent of footrot in sheep, correlates with inter-country movements [PDF]

, 2013
Dichelobacter nodosus is a Gram-negative, anaerobic bacterium and the causal agent of footrot in sheep. Multiple locus variable number tandem repeat (VNTR) analysis (MLVA) is a portable technique that involves the identification and enumeration of ...
Russell, Claire L, Wellington, Elizabeth MH, Moore, Lynda J, Grogono-Thomas, Rosemary, Green, Laura E.; id_orcid, Calvo-Bado, Leonides A, Medley, Graham F., Wellington, Elizabeth M.H., Moore, Lynda J., Medley, Graham F, Calvo-Bado, Leonides A., Wellington, Elizabeth M H, Smith, Edward M., Calvo-Bado, Leo A., Green, Laura E, Medley, Graham, Russell, Claire L., Green, Laura E., Wellington, E. M. H., Smith, Edward M   +19 more
core   +1 more source

Tandem repeats of the 5′ flanking region of human MUC5AC have a role as a novel enhancer in MUC5AC gene expression

Biochemistry and Biophysics Reports, 2019
MUC5AC is a well-known gastric differentiation marker, which has been frequently used for the classification of stomach cancer. However, the molecular mechanism of regulation of MUC5AC expression remains to be elucidated.
Natsuko Kageyama-Yahara, Nobutake Yamamichi, Yu Takahashi, Chihiro Takeuchi, Yuta Matsumoto, Yoshiki Sakaguchi, Kazuhiko Koike   +6 more
doaj   +1 more source