Results 61 to 70 of about 13,761 (295)

Space Telecommunications Radio System (STRS) Architecture [PDF]

, 2012
Space Telecommunications Radio System (STRS) Architecture Standard provides a NASA standard for software-defined radio. STRS is being demonstrated in the Space Communications and Navigation (SCaN) Testbed formerly known as Communications, Navigation and ...
Mortensen, Dale J., Briones, Janette C., Handler, Louis M., Reinhart, Richard C.   +3 more
core  

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Effectiveness and tolerance of single tablet versus once daily multiple tablet regimens as first-line antiretroviral therapy - Results from a large french multicenter cohort study.

PLoS ONE, 2017
ObjectivesPill burden during antiretroviral treatment (ART) is associated with worse adherence and impaired virological suppression. We compared the effectiveness, tolerance, and persistence on treatment of single tablet regimens (STRs) with non-STR once-
Laurent Cotte, Tristan Ferry, Pascal Pugliese, Marc-Antoine Valantin, Clotilde Allavena, André Cabié, Isabelle Poizot-Martin, David Rey, Claudine Duvivier, Antoine Cheret, Pierre Dellamonica, Pierre Pradat, Jean-Jacques Parienti, Dat’AIDS study group   +13 more
doaj   +1 more source

Multiple genetic analyses for Chinese Hunan Han population via 46 A-STRs

Annals of Human Biology, 2022
Background Short tandem repeats (STRs) are important as common genetic markers in forensic identification and population genetics due to their highly polymorphic nature.
Yunying Zhang, Yating Fang, Man Chen, Ming Zhao, Hui Xu, Congying Zhao, Jiangwei Lan, Bofeng Zhu   +7 more
doaj   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

Molecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou, Niki Tzenaki, Anna Tsapara, Maria Tzardi, Evangelia A. Papakonstanti   +4 more
wiley   +1 more source

Y chromosome SNPs and STRs

, 2011
The file contains 17 SNPs loci and 14 STRs ...
Anyaele, Okorie, Chiara Batini (3259911), Ferri, Gianmarco, Marcari, Veronica, Okorie Anyaele (3259914), Giovanni Destro-Bisol (2744287), Veronica Marcari (3259917), David Comas (31855), Valeria Montano (460596), Destro-Bisol, Giovanni, Batini, Chiara, Comas, David, Montano, Valeria, Gianmarco Ferri (281845)   +13 more
core   +1 more source

Detailed information concerning all 202 CSYseq targeted Y-STRs.

, 2021
Detailed information concerning all 202 CSYseq targeted Y-STRs.
Simon Vanpaemel (11401754), Maarten Larmuseau (3264285), Paulien Verstraete (11401748), Ronny Decorte (655794), Sofie Claerhout (155858), Liesbeth Warnez (11401751)   +5 more
core   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

Molecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth, Rui P. L. Neves, Julia Geheb, Christian Ballmeyer, Nathalie Gaßmann, Kiki C. Andree, Monica Sudarsanam, Christiane Driemel, Celine Örencik, Andrè Franken, Eslam Elmaghraby, Sven H. Loosen, Roderburg Christoph, Sebastian Schoelch, Hans Neubauer, Wolfram T. Knoefel, Nikolas H. Stoecklein, Georg Fluegen   +17 more
wiley   +1 more source

STRS SpaceWire FPGA Module [PDF]

, 2011
An FPGA module leverages the previous work from Goddard Space Flight Center (GSFC) relating to NASA s Space Telecommunications Radio System (STRS) project.
Lux, James P., Lang, Minh, Stern, Ryan A., Taylor, Gregory H.   +3 more
core