Results 51 to 60 of about 76,107 (347)

Avaliação da estrutura genética da população atual de Santa Catarina com diferentes marcadores moleculares para aplicação na genética forense [PDF]

, 2014
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas, Programa de Pós-Graduação em Biologia Celular e do Desenvolvimento, Florianópolis, 2014A identificação genética humana está centrada na utilização de um conjunto de
Torres, Sandra Regina Rachadel
core  

STRs data and pedigree analysis.

, 2022
(A) STRs data analysed on GeneMarker Software, with HBB5178, D11S1760, HBB5576, HBB5205 in blue, and D11S1243, HBB5138 in green; (B) Pedigree analysis of Couple 15, with mutated allele received from the mother (in red) and the father in (blue).
The-Hung Bui (6760736), Phuong Le Thi (321683), Thinh Huy Tran (14232206), Nha Nguyen Thi (14232212), Thanh Van Ta (6760739), Vu Viet Ha Vuong (14232203), Phuoc-Dung Nguyen (14232209), Manh-Ha Nguyen (14232218), Dang Thi Minh Nguyet (14232215), Van-Khanh Tran (14232221)   +9 more
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Adaptive Congestion Detection and Traffic Control in Software-Defined Networks via Data-Driven Multi-Agent Reinforcement Learning

Computers
Efficient congestion management in Software-Defined Networks (SDNs) remains a significant challenge due to dynamic traffic patterns and complex topologies.
Kaoutar Boussaoud, Abdeslam En-Nouaary, Meryeme Ayache   +2 more
doaj   +1 more source

Rapidly mutating Y-STRs in rapidly expanding populations: Discrimination power of the Yfiler Plus multiplex in northern Africa.

Forensic Science International: Genetics, 2019
The male-specific northern African genetic pool is characterised by a high frequency of the E-M81 haplogroup, which expanded in very recent times (2-3 kiloyears ago).
Eugenia D’Atanasio, G. Iacovacci, Rossella Pistillo, Mariana Bonito, J. Dugoujon, P. Moral, F. El-Chennawi, M. Melhaoui, A. Baali, M. Cherkaoui, D. Sellitto, B. Trombetta, A. Berti, F. Cruciani   +13 more
semanticscholar   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Massively parallel sequencing of autosomal STRs and identity-informative SNPs highlights consanguinity in Saudi Arabia.

Forensic Science International: Genetics, 2019
While many studies have been undertaken of Middle Eastern populations using autosomal STR profiling by capillary electrophoresis, little has so far been published from this region on the forensic use of massively parallel sequencing (MPS).
Yahya M. Khubrani, P. Hallast, M. Jobling, J. Wetton   +3 more
semanticscholar   +1 more source

Population genetic analysis of 12 X-chromosomal STRs in a Swiss sample. [PDF]

, 2022
X-chromosomal STRs are a powerful tool to assess a broad variety of complex kinship scenarios. We introduce herewith the first Swiss X-STR dataset based on 1198 individuals (592 female, 606 male), characterized with the Qiagen Investigator® Argus X-12 QS
Bottinelli, Michel, Gouy, Alexandre, Utz, Silvia, Zieger, Martin   +3 more
core   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Population genetic data of the 21 autosomal STRs included in GlobalFiler kit of a population sample from the Kingdom of Bahrain

bioRxiv, 2019
Introduction Bahrain’s population consists mainly of Arabs, Baharna and Persians leading Bahrain to become ethnically diverse. The exploration of the ethnic origin and genetic structure within the Bahraini population is fundamental mainly in the field of
Noora R. Al-Snan, Safia A. Messaoudi, S. Babu, M. Bakhiet   +3 more
semanticscholar   +1 more source