Results 191 to 200 of about 69,991 (228)
British Educational Research Journal, EarlyView.Abstract The study used descriptive and multivariate statistics analytical methods to explore relationships between the highest level of education expected by 15‐year‐old Romanian students and factors associated with student background (personal and academic), school characteristics and selected beliefs and social–emotional skills.
Camelia Truța +4 more
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British Educational Research Journal, EarlyView.Abstract Drawing upon interview research across two academic departments as part of the early stages of a ‘decolonise the curriculum’ initiative at a Southern UK university, this study highlights a growing gulf between policy and practice in efforts to address systemic racial inequalities in UK universities. A reliance upon precarious labour, a culture
Triona Fitton +4 more
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Exosome as bioactive nanovesicle for diagnostic and therapeutic applications in periodontitis
BMEMat, EarlyView.This review introduces the mechanism that exosomes participate in the pathogenesis of periodontitis and their potential as biomarkers for early diagnosis and summarizes the application of cell‐ or plant‐derived exosomes or engineered exosomes in periodontitis or periodontal regeneration while proposing the perspective of translational application of ...
Yu Wang +6 more
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Review of the book Organisaties vergelijkenderwijs: Ontwikkeling en relevantie van het sociologisch denken over organisaties, C.J. Lammers, 1983, 902746507X. [PDF]
Pennings, J.M.
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Annual Reports to the ESA Council ESA 110th Annual Meeting July, 2025
The Bulletin of the Ecological Society of America, EarlyView.
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Mutagenic potential and structural alerts of phytotoxins
Food and Chemical Toxicology, 2023Toxic plant-produced chemicals, so-called phytotoxins, constitute a category of natural compounds belonging to a diversity of chemical classes. Some of them (e.g., alkaloids, terpenes, saponins) are associated with high toxic potency, while for many of others no toxicological data is available. In this study, the mutagenic potential of 1586 phytotoxins,
Arianna Bassan +2 more
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From Structural Alerts to Signature Fragment Alerts: A Case Study on Pyrrolizidine Alkaloids
Chemical Research in Toxicology, 2023Even though modeling is considered a valid alternative to mutagenicity testing for substances with known structures, it can be applied for mixtures only if all of the single chemical structures are identified. Within the present work, we investigate a new avenue to exploit computational toxicology for mixtures, such as plant-based food ingredients ...
Elena Lo Piparo +2 more
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Skin sensitization quantitative QSAR models based on mechanistic structural alerts
Toxicology, 2022Allergic contact dermatitis is increasingly of interest for the hazard characterization of chemicals. in vivo animal testing is usually adopted but in silico approaches are becoming the new frontier due to their swiftness and economic efficiency. Indeed, in silico models can rationalise the experimental outcomes besides having predictive ability.
Chayawan, +6 more
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Structural Alerts of Mutagens and Carcinogens
Current Computer Aided-Drug Design, 2006This paper summarizes the evidence on the Structural Alerts of mutagenicity and carcinogenicity. The Structural Alerts are molecular substructures or reactive groups that are related to the carcinogenic and mutagenic properties of the chemicals, and represent a sort of "codification" of a long series of studies aimed at highlighting the mechanisms of ...
Romualdo Benigni, Cecilia Bossa
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Azaindolines: derisking the indoline structural alert
Tetrahedron Letters, 2012Abstract 4-Substitued azaindolines, which are isosteres of indolines, are useful synthetic building blocks that reduce the risk of bioactivation induced idiosyncratic toxicity have been prepared. Multigram routes to 2,3-dihydro-1H-pyrrolo[2,3-c]pyridine-4-triflate 16, 2,3-dihydro-1H-pyrrolo[2,3-b]pyridine-4-carbonitrile 20 and 4-chloro-2,3-dihydro-1H-
Eugene L. Piatnitski Chekler +6 more
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