Results 61 to 70 of about 69,991 (228)

ALS With and Without Upper Motor Neuron Signs: A Comparative Study Supporting the Gold Coast Criteria

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The Gold Coast criteria permit diagnosis of amyotrophic lateral sclerosis (ALS) even without upper motor neuron (UMN) signs. However, whether ALS patients with UMN signs (ALSwUMN) and those without (ALSwoUMN) share similar characteristics and prognoses remains unclear.
Hee‐Jae Jung   +7 more
wiley   +1 more source

In silico toxicological risk assessment of chemical constituents from Curtisia dentata stem-bark extract

open access: yesToxicology Reports
Herbal products are widely used in healthcare due to their therapeutic potential. However, concerns persist among medicinal chemists and regulatory toxicologists regarding their safety and potential toxicity.
Anna S. van Wyk   +3 more
doaj   +1 more source

Mutagenic and carcinogenic structural alerts and their mechanisms of action [PDF]

open access: yesArchives of Industrial Hygiene and Toxicology, 2016
AbstractKnowing the mutagenic and carcinogenic properties of chemicals is very important for their hazard (and risk) assessment. One of the crucial events that trigger genotoxic and sometimes carcinogenic effects is the forming of adducts between chemical compounds and nucleic acids and histones.
Alja, Plošnik   +2 more
openaire   +2 more sources

Making 'The Daily Me': Technology, economics and habit in the mainstream assimilation of personalized news [PDF]

open access: yes, 2011
The mechanisms of personalization deployed by news websites are resulting in an increasing number of editorial decisions being taken by computer algorithms — many of which are under the control of external companies — and by end users.
Thurman, N.
core   +2 more sources

Computing similarity between structural environments of mutagenicity alerts

open access: yesMutagenesis, 2018
This article describes a method to generate molecular fingerprints from structural environments of mutagenicity alerts and calculate similarity between them. This approach was used to improve classification accuracy of alerts and for searching structurally similar analogues of an alerting chemical.
Suman K, Chakravarti   +1 more
openaire   +2 more sources

Smart, Bio‐Inspired Polymers and Bio‐Based Molecules Modified by Zwitterionic Motifs to Design Next‐Generation Materials for Medical Applications

open access: yesAdvanced Functional Materials, EarlyView.
Bio‐based and (semi‐)synthetic zwitterion‐modified novel materials and fully synthetic next‐generation alternatives show the importance of material design for different biomedical applications. The zwitterionic character affects the physiochemical behavior of the material and deepens the understanding of chemical interaction mechanisms within the ...
Theresa M. Lutz   +3 more
wiley   +1 more source

Cool Kitchen: Processing Starch and Eggshell Powder into Sustainable Coatings for Passive Daytime Cooling

open access: yesAdvanced Functional Materials, EarlyView.
A food‐grade cooling composite made from starch and recycled eggshell powder offers a scalable, ultra‐low‐cost solution for passive daytime radiative cooling. Easily prepared using basic kitchen tools, this material empowers communities, even in areas with limited infrastructure, to stay cooler during worsening summer heat waves.
Qimeng Song   +3 more
wiley   +1 more source

Exploring Patterns in Quality Alerts via Random Forest and Multiple Correspondence Analysis

open access: yesApplied Sciences
This study presents a multivariate and machine learning-based approach to analyze quality alerts in an industrial manufacturing context. Based on data from recorded quality alerts, this research integrates exploratory data analysis, Multiple ...
Iliana Ramírez-Velásquez   +3 more
doaj   +1 more source

Generating Cell Surface Nucleated Hydrogels with an Artificial Membrane‐Binding Transglutaminase

open access: yesAdvanced Functional Materials, EarlyView.
Cell‐based therapies require advanced strategies to enhance cell delivery and bioactivity. Cell membrane engineering offers an avenue to impart new functions to delivered cells to boost their viability and function. Here, an artificial membrane‐binding transglutaminase is generated and biophysically characterized.
Rosalia Cuahtecontzi Delint   +6 more
wiley   +1 more source

Assessment of performance of the profilers provided in the OECD QSAR toolbox for category formation of chemicals

open access: yesScientific Reports
Growing restrictions and bans on animal testing for chemical safety assessment under different regulations have led to an increasing use of alternative methods.
Mohammed Abdulaziz Aljallal   +2 more
doaj   +1 more source

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