Results 51 to 60 of about 6,791,323 (278)
The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity
FEBS Letters, EarlyView.The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley +1 more source
Measurement and identification of ice loads on hull structures in far field based on dynamic effects
Zhongguo Jianchuan Yanjiu, 2021 ObjectivesThis study presents an identification method for ice loads which takes the dynamic effect into consideration. Methods Due to the convolution relation between ice-ship interaction and structural response, the ice load described by the ...
Shuaikang HE +3 more
doaj +1 more source
Molecular bases of circadian magnesium rhythms across eukaryotes
FEBS Letters, EarlyView.Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
Design of FRP reinforced concrete beams for serviceability requirements
Journal of Civil Engineering and Management, 2012 Serviceability Limit States (SLS) may govern the design of concrete elements internally reinforced with Fibre Reinforced Polymer (FRP) bars because of the mechanical properties of FRP materials.
Cristina Barris +3 more
doaj +1 more source
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
Structural analysis of Salmonella enterica effector protein SopD [PDF]
, 2004 Salmonella outer protein D (SopD) is a type III secreted virulence effector protein from Salmonella enterica. Full-length SopD and SopD lacking 16 amino acids at the N-terminus (SopDDeltaN) have been expressed as fusions with GST in Escherichia coli ...
Bagby, S +7 more
core +1 more source
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Structural Analysis and Religiosity of Balinese Song Lyrics [PDF]
, 2018 This study examines the lyrics of Balinese religious songs with a primary focus on analyzing the various forms of microstructure, macrostructure, and superstructure of Balinese religious songs by using the Van Dijk discourse analysis.
Mantra, I. B. (Ida) +1 more
core
Structural models and structural change: analytical principles and methodological issues [PDF]
, 1992 Structural analysis is the main topic of this paper and structural change is a dominant theme of the present work. The analysis of structural models and of theories of structural changes carried out in this paper has a double meaning.
Schilirò, Daniele
core +3 more sources
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source