Results 81 to 90 of about 650,868 (292)

High-resolution NMR reveals secondary structure and folding of amino acid transporter from outer chloroplast membrane. [PDF]

open access: yesPLoS ONE, 2013
Solving high-resolution structures for membrane proteins continues to be a daunting challenge in the structural biology community. In this study we report our high-resolution NMR results for a transmembrane protein, outer envelope protein of molar mass ...
James D Zook   +7 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Kalman state estimator for aircraft structural load alleviation using eigenpair assignment

open access: yesResults in Control and Optimization
Process of finding the “best estimate” from noisy signals amounts to “filtering out” the noise. Many methods exist to filter the unwanted noise. A tried and tested method is to use a Kalman Filter which not only cleans up the signals but can also be used
Rashid Ali
doaj   +1 more source

Robust Assignment of Natural Frequencies and Antiresonances in Vibrating Systems through Dynamic Structural Modification

open access: yesShock and Vibration, 2021
This paper proposes a novel method for the robust partial assignment of natural frequencies and antiresonances, together with the partial assignment of the related eigenvectors, in lightly damped linear vibrating systems.
Roberto Caracciolo   +2 more
doaj   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

Modélisation de répartition d’élèves et délimitation de secteurs scolaires en milieu urbain

open access: yesBelgeo, 2017
In the midst of a school reform context and following its continuous population growth, the city of Lausanne had to re-examine various aspects of the management of its public schools.
Théophile Emmanouilidis
doaj   +1 more source

SubCMap: subject and condition specific effect maps [PDF]

open access: yes, 2017
Current methods for statistical analysis of neuroimaging data identify condition related structural alterations in the human brain by detecting group differences. They construct detailed maps showing population-wide changes due to a condition of interest.
Glocker, B, Konukoglu, E
core  

Structural Decompositions for Problems with Global Constraints

open access: yes, 2015
A wide range of problems can be modelled as constraint satisfaction problems (CSPs), that is, a set of constraints that must be satisfied simultaneously.
Thorstensen, Evgenij
core   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Interaction of aluminium hydrolytic species with biomolecules [PDF]

open access: yes, 2008
In this contribution the formation of bioinorganic assemblies between the basic globular protein lysozyme and aqueous aluminium species including Al 13 -mer, Al 30 -mer and colloidal aluminium hydroxide have been explored and comparison made to previous ...
Deschaume, O   +3 more
core  

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