Results 31 to 40 of about 273,506 (260)

Structural analysis of nucleosomal barrier to transcription [PDF]

Proceedings of the National Academy of Sciences, 2015
Significance On the majority of eukaryotic genes RNA polymerase II meets nucleosomes during transcription of every ∼200 bp of DNA. The key features of Pol II–nucleosome encounter are conserved from yeast to human, but the molecular mechanism of this process remains unknown.
Daria A, Gaykalova, Olga I, Kulaeva, Olesya, Volokh, Alexey K, Shaytan, Fu-Kai, Hsieh, Mikhail P, Kirpichnikov, Olga S, Sokolova, Vasily M, Studitsky   +7 more
openaire   +2 more sources

Improved Early Referral in Long‐Term Survivor Care With Institutional Standardized Practice Among Childhood Leukemia Survivors#

Pediatric Blood &Cancer, EarlyView.
ABSTRACT In 2018, the Texas Children's Cancer and Hematology Center Leukemia Program implemented a practice standard to support the transition from treatment to survivorship that includes shared, alternating care between leukemia and survivorship clinicians and a reminder to refer survivors to the long‐term survivor clinic (LTSC) 2 years after ...
Ji Yun Tark, Kayla L. Foster, Omar Shakeel, Mary C. Shapiro, Shawki L. Qasim, ZoAnn Dreyer, Eric S. Schafer, Ashley M. Butler, Austin L. Brown, Maria Monica Gramatges   +9 more
wiley   +1 more source

Early Impact of Childhood Opportunity on Neurocognitive Outcomes in Sickle Cell Disease

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Neurocognitive impairment is a well‐recognized complication of sickle cell disease (SCD) that begins early in childhood and persists across development. While cerebrovascular injury contributes substantially to risk, neurocognitive deficits are also observed in children without overt or silent cerebral infarctions, suggesting ...
Julia E. LaMotte, Hannah Koch, Olivia A. Coughlin, Jillian R. Bouck, Allie Carter, Seethal A. Jacob   +5 more
wiley   +1 more source

Spanoids---An Abstraction of Spanning Structures, and a Barrier for LCCs [PDF]

SIAM Journal on Computing, 2020
Conference version to appear in ITCS 2019.
Dvir, Zeev, Gopi, Sivakanth, Gu, Yuzhou, Wigderson, Avi   +3 more
openaire   +4 more sources

Ironic Medications: A Narrative‐Based Psycho‐Educational Intervention to Explore Patient–Provider Communication in Adolescents With Haematological Cancer

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Adolescents with haematological malignancies face significant emotional and relational challenges, often accompanied by difficulties in communicating their needs within the healthcare context. To address these issues, a narrative‐based psycho‐educational intervention based on the creation and prescription of Ironic Medications was ...
Marta Stoppa, Elena Pagani Bagliacca, Selena Russo, Giulia Rampoldi, Maria Grazia Strepparava, Adriana Cristina Balduzzi, Andrea Biondi, Marco Spinelli   +7 more
wiley   +1 more source

Incidence and Severity of Carboplatin‐Associated Hearing Loss in Children With Cancer Assessed by the SIOP Boston 2012 Ototoxicity Criteria

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Platinum‐based chemotherapy is known to cause severe and debilitating hearing loss, but unlike cisplatin, the true incidence of carboplatin‐induced hearing loss remains unclear. We evaluated functional hearing outcomes in children receiving carboplatin to determine the incidence and severity of ototoxicity. Procedure We identified a
Aniket Chawla, Sean Carter, Andrew Wood, Sandra Staffieri, Andrew Dodgshun, David D. Eisenstat, Michael Sullivan   +6 more
wiley   +1 more source

Barriers for Virtual Assessment of Structural Robustness [PDF]

Volume 2B: Advanced Manufacturing, 2019
Abstract Simulation techniques such as Finite Element Analysis (FEA) have substantially contributed to reducing the time and cost of developing new mechanical products over the last decades. However, FEA is primarily carried out on the nominal geometry, i.e.
Nerenst, Tim Brix, Ebro, Martin, Nielsen, Morten, Eifler, Tobias; id_orcid 0000-0002-1293-3313, Nielsen, Kim Lau; id_orcid 0000-0002-0502-8008   +4 more
openaire   +2 more sources

BMT4me En Español: Multisite Feasibility and Usability Testing of a Spanish‐Language mHealth Adherence Support App for Spanish‐Speaking Caregivers of Children After Hematopoietic Stem Cell Transplantation and Cancer Treatment

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Medication nonadherence during the first 100 days after pediatric hematopoietic stem cell transplantation (HSCT) and during oncology treatment increases risk for complications. BMT4me is a caregiver‐facing mobile health (mHealth) application providing medication reminders, symptom tracking, and note‐taking features to support ...
Micah A. Skeens, Madeline R. Peek, Bianca Franklin, Emre Sezgin, Melissa Beauchemin   +4 more
wiley   +1 more source

Grounded theory assessment of health needs in rural Mississippi Delta region, USA: Implications for health policy and management [PDF]

Journal of Health and Social Sciences
Introduction: The Mississippi Delta is the most rural and economically disadvantaged area in the United States. Rural communities face challenges in accessing quality healthcare for chronic illnesses and diseases.
Yalanda M. BARNER, Austine U. ONYIA, Russell L. BENNETT, Manoj SHARMA   +3 more
doaj  

Barriers beyond behavior: structural determinants of behavioral health treatment disparities among Hispanics in the U.S.

Frontiers in Public Health
BackgroundPersistent disparities in substance use treatment access undermine efforts to achieve equitable public health outcomes in the United States. Hispanic populations, who report lower prevalence of substance use, nevertheless face systemic barriers
Marissa Gonzalez, Jose Eduardo Cabrero Castro, Emre Umucu, Alfonso Rojas-Alvarez   +3 more
doaj   +1 more source