Results 111 to 120 of about 644,547 (283)
THE CAUSAL STRUCTURE OF LAND PRICE DETERMINANTS [PDF]
This paper investigates causation contemporaneously and over time to elucidate the persistent lack of agreement about what "causes" changes in farmland prices.
Awokuse, Titus O., Duke, Joshua M.
core +1 more source
Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae
FEBS Open Bio, EarlyView.Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj +3 more
wiley +1 more source
FEBS Open Bio, EarlyView.dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon +6 more
wiley +1 more source
FEBS Open Bio, EarlyView.Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley +1 more source
Extremes of structural causal models
The behavior of extreme observations is well-understood for time series or spatial data, but little is known if the data generating process is a structural causal model (SCM). We study the behavior of extremes in this model class, both for the observational distribution and under extremal interventions. We show that under suitable regularity conditions
Engelke, Sebastian +2 more
openaire +3 more sources
Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control
FEBS Open Bio, EarlyView.Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada +5 more
wiley +1 more source
ipw: An R Package for Inverse Probability Weighting
Journal of Statistical Software, 2011 We describe the R package ipw for estimating inverse probability weights. We show how to use the package to fit marginal structural models through inverse probability weighting, to estimate causal effects.
Ronald B. Geskus, Willem M. van der Wal
doaj
Individual Causal Inference with Structural Causal Model
Individual causal inference (ICI) uses causal inference methods to understand and predict the effects of interventions on individuals, considering their specific characteristics / facts. It aims to estimate individual causal effect (ICE), which varies across individuals.
openaire +2 more sources
FEBS Open Bio, EarlyView.Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn +4 more
wiley +1 more source
Juventude, trabalho e desenvolvimento: elementos para uma agenda de investigação
Caderno CRHA crise econômica pós-2008, acompanhada de grandes protestos sociais em toda parte, acendeu a luz vermelha nos países mais ricos quanto às oportunidades de trabalho e estudo dos jovens.
Adalberto Cardoso
doaj +1 more source