Results 51 to 60 of about 1,527,783 (278)

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Structural Constraints in Postsecondary Education: Capacity and Financial Aid [PDF]

, 2006
Includes presentation materials on advocacy options to help increase public higher education capacity and secure financial aid for low-income students in order to meet increasing demand as high school graduation rates rise as a result of ...

core  

Interface Problems: Structural Constraints on Interpretation? [PDF]

Journal of Psycholinguistic Research, 2005
Five experiments investigated the interpretation of quantified noun phrases in relation to discourse structure. They demonstrated, using questionnaire and on-line reading techniques, that readers in English prefer to give a quantified noun phrase in (VP-external) subject position a presuppositional interpretation, in which the noun phrase limits or ...
Frazier, Lyn, Clifton Jr., C., Rayner, K., Deevt, P., Koh, S., Bader, M.   +5 more
openaire   +2 more sources

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Structural Capacity Constraints in Australia’s Housing Crisis: A System Dynamics Analysis of the National Housing Accord’s Unachievable Targets

Systems
Australia’s National Housing Accord aims to deliver 1.2 million new dwellings between mid-2024 and mid-2029, representing 240,000 annual completions—a 37% increase above the 2024 baseline of 175,000.
Gavin Melles
doaj   +1 more source

(De)Constructing Conflict: A Focused Review of War and Peace Journalism [PDF]

Conflict & Communication Online, 2006
This overview of the media and conflict literature and case study of media coverage of peace offers a framework and guidance for peace journalism. Many studies show media rarely report conflict neutrally.
Susan Dente Ross
doaj  

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source

GERMANY’S LABOUR SHORTAGE: BETWEEN STRUCTURAL PRESSURE AND UNCERTAIN HORIZONS [PDF]

Global Economic Observer
Germany is currently facing a profound labour shortage that transcends sectoral boundaries and reflects deeper demographic and structural transformations. Following a brief post-pandemic rebound, the German economy has entered a phase of stagnation and
ANA-CRISTINA BÂLGĂR
doaj  

Energy optimization through morphing blade design under structural constraints: a case study on the NREL 1.5 MW wind turbine

Science and Technology for Energy Transition
This study explores a novel morphing blade design methodology to enhance the aerodynamic performance of the NREL 1.5 MW wind turbine while addressing structural constraints.
Najafian Arezoo, Jahangirian Alireza
doaj   +1 more source