Results 41 to 50 of about 4,022,588 (277)
The Potential of Self-Tempered Martensite and Bainite in Improving the Fatigue Strength of Thermomechanically Processed Steels [PDF]
MATEC Web of Conferences, 2018 In contrast to a two-stage hardening and tempering process, the definition of optimized cooling routes after hot working of low-alloy Cr steel allows the adjustments of high-strength microstructures with a sufficient degree of ductility at the same time ...
Krupp Ulrich +4 more
doaj +1 more source
Space shuttle orbiter leading-edge flight performance compared to design goals [PDF]
, 1983 Thermo-structural performance of the Space Shuttle orbiter Columbia's leading-edge structural subsystem for the first five (5) flights is compared with the design goals.
Curry, D. M. +2 more
core +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Challenging Glass Conference Proceedings, 2020 Laminated safety glass (LSG) is increasingly used as structural element in buildings. Of central importance for safety are the adhesion and the residual load-bearing capacity in the post fractured state.
Miriam Schuster +2 more
doaj
Which experimental procedures influence the apparent proximal femoral stiffness? A parametric study
BMC Musculoskeletal Disorders, 2021 Background Experimental validation is the gold standard for the development of FE predictive models of bone. Employing multiple loading directions could improve this process.
Morteza Amini +3 more
doaj +1 more source
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Automated fully-stressed design with NASTRAN [PDF]
, 1976 An automated strength sizing capability is described. The technique determines the distribution of material among the elements of a structural model.
Haggenmacher, G. W., Wallerstein, D. V.
core +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source