Results 101 to 110 of about 3,458,614 (298)

Trapping and Structural Elucidation of a Very Advanced Intermediate in the Lesion-Extrusion Pathway of hOGG1

open access: yes, 2016
Trapping and Structural Elucidation of a Very Advanced Intermediate in the Lesion-Extrusion Pathway of ...
Christopher T. Radom (2433430)   +2 more
core   +1 more source

Structure elucidation and antioxidant activity of anthraquinon derivate from Cassia alata Linn [PDF]

open access: yes, 2020
Structure elucidation and antioxidant activity of anthraquinon derivate from Cassia alata ...
Santoni, Adlis
core  

Separation and Structural Elucidation of Xenobiotics in the Pico- to Nanogram Scale [PDF]

open access: yes, 1999
Structural elucidation and quantification of complex mixtures of organic compounds is a real challenge when i) the substance amount approaches the pg to ng range, ii) a lot of closely related structures are present, and iii) when no special structure ...
Michael Oehme, Oehme, Michael
core   +1 more source

Synthesis, Structural Confirmation, and Biosynthesis of 22-OH-PD1n-3 DPA

open access: yesMolecules, 2019
PD1n-3 DPA belongs to the protectin family of specialized pro-resolving lipid mediators. The protectins are endogenously formed mediators that display potent anti-inflammatory properties and pro-resolving bioactivities and have attracted interest in drug
Jannicke Irina Nesman   +5 more
doaj   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Spectral Analyses of Ecabet Sodium

open access: yesChinese Journal of Magnetic Resonance, 2018
Ultraviolet (UV) spectrum, infrared (IR) spectrum, high resolution-mass spectrum (HR-MS), nuclear magnetic resonance (NMR) spectra (i.e., 1H NMR, 13C NMR, DEPT, 1H-1H COSY, 1H-13C HSQC and 1H-13C HMBC) of ecabet sodium were collected and analyzed to ...
JI Xiao-long, YU Shui-tao, CHEN Zai-xin
doaj   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

open access: yesMolecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla   +4 more
wiley   +1 more source

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Elucidating the Structure of Membrane Proteins [PDF]

open access: yesBioTechniques, 2019
Joseph Martin, Abigail Sawyer
openaire   +2 more sources

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

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