Results 81 to 90 of about 234,776 (300)
Spectral Analysis and Structural Elucidation of Besifloxacin Hydrochloride
Chinese Journal of Magnetic Resonance, 2018 The ultraviolet spectra (UV), infrared spectra (IR), mass spectra (MS) and nuclear magnetic resonance (NMR) spectra (i.e., 1H NMR, 13C NMR, DEPT, HSQC, HMBC, COSY and NOESY) of besifloxacin hydrochloride were acquired and interpreted.
ZHANG Ming-guang +4 more
doaj +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Phocoenamicins B and C, New Antibacterial Spirotetronates Isolated from a Marine Micromonospora sp.
Marine Drugs, 2018 Phocoenamicins B and C (1 and 2), together with the known spirotetronate phocoenamicin (3), were isolated from cultures of Micromonospora sp. The acetone extract from a culture of this strain, isolated from marine sediments collected in the Canary ...
Mercedes Pérez-Bonilla +7 more
doaj +1 more source
How do nematodes transfer phosphorylcholine to carbohydrates? [PDF]
, 2010 An unusual aspect of the biology of nematodes is the attachment of phosphorylcholine (PC) to carbohydrate. The attachment appears to play an important role in nematode development and, in some parasitic species, in immunomodulation.
Harnett, W., Houston, K.M., Rzepecka, J.
core +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
PlantsA total of 31 compounds were isolated from the ethyl acetate and n-butanol fractions of Anchusa italica Retz., which contained one ursane triterpenoid, 2α,3β,19α-trihydroxy-23-formyl-urs-12-en-28,21β-olide (1), and five norisoprenoids: (2R,6R,9S)-9 ...
Linchuang Shen +8 more
doaj +1 more source
Local Structural Features Elucidate Crystallization of Complex Structures
ACS Nano38 pages, 6 figures, 80 ...
Maya M. Martirossyan +3 more
openaire +3 more sources
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Pyridoacridine alkaloids from deep-water marine organisms: Structural elucidation
Bulletin of Faculty of Pharmacy Cairo University, 2016 Pyridoacridine alkaloids are unique marine nitrogenous compounds that represent a large family of alkaloids. They have been reported from different marine organisms like sponges, ascidians, anemones, prosobranch mollusk, and tunicates.
Sabrin R.M. Ibrahim, Gamal A. Mohamed
doaj +1 more source
The isolation and structural elucidation of voacristine hydroxyindolenine [PDF]
Isolation and characterization of voacristine ...
Aksornvitaya, R. +4 more
core +1 more source