Results 91 to 100 of about 1,027,895 (271)

Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence

open access: yesMolecular Oncology, EarlyView.
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova   +18 more
wiley   +1 more source

Exchange requirement-based delivery method of structural design information for collaborative design using industry foundation classes

open access: yesJournal of Civil Engineering and Management, 2019
In Architecture, engineering, and construction (AEC) collaboration, exchange requirements (ERs) vary in different projects with different platforms. In order to ensure the completeness and accuracy of data sharing and exchange for structural engineering ...
Huahui Lai, Cheng Zhou, Xueyuan Deng
doaj   +1 more source

Structural engineer to structural engineer: conversation with Steve Johnston [PDF]

open access: yesThe Structural Design of Tall Buildings, 2001
Chris D. Poland, James O. Malley
openaire   +2 more sources

Application Of Structural Control For Civil Engineering Structures

open access: yes, 2008
This study presents the application of control methods in seismic mitigation of structural responses. The study consists of two parts. In the first section, fractional order filters are utilized to enhance the performance of the conventional LQR method for optimal robust control of a simple civil structure.
openaire   +3 more sources

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

open access: yesMolecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu   +12 more
wiley   +1 more source

Understanding and measuring mechanical signals in the tumor stroma

open access: yesFEBS Open Bio, EarlyView.
This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz   +3 more
wiley   +1 more source

Study on energy conservation and carbon emission reduction design of timber structure building

open access: yesThe Journal of Engineering, 2019
Replacing traditional building materials with renewable and sustainable materials such as timber can control environmental pollution such as energy consumption and carbon emission in the whole life cycle of a building, which is conducive to energy ...
Miao Yue   +5 more
doaj   +1 more source

Applying Agile Requirements Engineering Approach for Re-engineering & Changes in existing Brownfield Adaptive Systems [PDF]

open access: yesarXiv, 2014
Requirements Engineering (RE) is a key activity in the development of software systems and is concerned with the identification of the goals of stakeholders and their elaboration into precise statements of desired services and behavior. The research describes an Agile Requirements Engineering approach for re-engineering & changes in existing Brownfield
arxiv  

A potential tumor suppressor role of PLK2 in glioblastoma

open access: yesFEBS Open Bio, EarlyView.
PLK2 was consistently downregulated in GBM tissues. Overexpression of PLK2 in GBM cell lines U87MG and U251 reduced their tumorigenic potential and enhanced cell cycle arrest and apoptosis. Suggesting that PLK2 overexpression could potentially be leveraged as a therapeutic strategy to inhibit tumor progression and enhance apoptosis, providing new ...
Xiangping Xia   +5 more
wiley   +1 more source

Editorial: Methods and applications in computational methods in structural engineering

open access: yesFrontiers in Built Environment, 2023
Alejandro Jiménez Rios   +3 more
doaj   +1 more source

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