Results 101 to 110 of about 8,779,764 (343)

Deflection characterisation of rotary systems using ground-based radar

open access: yesThe Journal of Engineering, 2019
In the last two decades, an increase in large rotary machines/systems has been witnessed. To ensure safe operation of these systems especially due to extreme stress caused by centrifugal forces as well as the wind or water loadings, regular structural ...
Francis X. Ochieng   +6 more
doaj   +1 more source

Structural analysis of silicon solar arrays [PDF]

open access: yes
Engineering mechanics in structural design of silicon solar ...
Butterworth, L. W., Yasui, R. K.
core   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Periodic Layout Optimization of Cyclic Symmetric Structure

open access: yesIEEE Access, 2019
This paper proposes a new optimization method to solve periodic layout optimization of a cyclic symmetric structure by means of the guide-weight method.
Hong-Yu Jiao, Ying Li, Lan-Yu Yang
doaj   +1 more source

Outer planet probe engineering model structural tests [PDF]

open access: yes
A series of proof of concept structural tests was performed on an engineering model of the Outer Planets Atmospheric Entry Probe. The tests consisted of pyrotechnic shock, dynamic and static loadings.
Griffin, M. W.   +2 more
core   +1 more source

Emerging artificial intelligence methods in structural engineering

open access: yesEngineering structures, 2018
Artificial intelligence (AI) is proving to be an efficient alternative approach to classical modeling techniques. AI refers to the branch of computer science that develops machines and software with human-like intelligence.
H. Salehi, R. Burgueño
semanticscholar   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Vulnerability and Robustness of Civil Infrastructure Systems to Hurricanes

open access: yesFrontiers in Built Environment, 2017
Civil infrastructure systems play an important role in community resilience. Without proper functioning of the infrastructure, especially power delivery, society will not recover quickly from disruptive events, such as hurricanes.
Shuoqi Wang, Dorothy A. Reed
doaj   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Exchange requirement-based delivery method of structural design information for collaborative design using industry foundation classes

open access: yesJournal of Civil Engineering and Management, 2019
In Architecture, engineering, and construction (AEC) collaboration, exchange requirements (ERs) vary in different projects with different platforms. In order to ensure the completeness and accuracy of data sharing and exchange for structural engineering ...
Huahui Lai, Cheng Zhou, Xueyuan Deng
doaj   +1 more source

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