Results 91 to 100 of about 8,779,764 (343)

Using Machine Learning Algorithms to Develop a Predictive Model for Computing the Maximum Deflection of Horizontally Curved Steel I-Beams

open access: yesComputation
Horizontally curved steel I-beams exhibit a complicated mechanical response as they experience a combination of bending, shear, and torsion, which varies based on the geometry of the beam at hand. The behaviour of these beams is therefore quite difficult
Elvis Ababu   +2 more
doaj   +1 more source

Verrouillage professionnel

open access: yesRevue d'anthropologie des connaissances, 2014
Recent challenges such as sustainable development and climate change suggest engineers to focus on societal issues. However, as this case study of structural design shows, professional arrangements within the construction field constrain engineers ...
Andrew Chilvers, Sarah Bell
doaj   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Designing by Geometry. Rankine's Theorems of Transformation of Structures. [PDF]

open access: yes, 2010
William John Macquorn Rankine (1820-1872) was one of the main figures in establishing engineering science in the second half of the 19th. Century. His Manual of Applied Mechanics (1858) gathers most of his contributions to strength of materials and ...
Huerta Fernández, Santiago
core   +1 more source

A Computationally Efficient Ground-Motion Selection Algorithm for Matching a Target Response Spectrum Mean and Variance [PDF]

open access: yes, 2011
Dynamic structural analysis often requires the selection of input ground motions with a target mean response spectrum. The variance of the target response spectrum is usually ignored or accounted for in an ad hoc manner, which can bias the structural ...
Baker, Jack W.   +2 more
core   +2 more sources

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Study on energy conservation and carbon emission reduction design of timber structure building

open access: yesThe Journal of Engineering, 2019
Replacing traditional building materials with renewable and sustainable materials such as timber can control environmental pollution such as energy consumption and carbon emission in the whole life cycle of a building, which is conducive to energy ...
Miao Yue   +5 more
doaj   +1 more source

Performance Assessment of Concrete Crack Repairing Materials using PZT Transducers [PDF]

open access: yes, 2018
Department of Urban and Environmental Engineering (Urban Infrastructure Engineering)Concrete is a widely used material in construction of civil infrastructure engineerings such as dams, houses, bridges, and energy plants.
Liu, Xiaoming
core  

Geotechnical design with apparent seismic safety factors well-bellow 1 [PDF]

open access: yes, 2014
The paper demonstrates that whereas often in seismic geotechnical design it is not realistically feasible to design with ample factor of safety against failure as is done in static design, an "engineering" apparent seismic factor of safety less than 1 ...
Anastasopoulos   +27 more
core   +3 more sources

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

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