Results 41 to 50 of about 568,488 (296)

Lignin structure and its engineering

open access: yesCurrent Opinion in Biotechnology, 2019
Studies on lignin structure and its engineering are inextricably and bidirectionally linked. Perturbations of genes on the lignin biosynthetic pathway may result in striking compositional and structural changes that in turn suggest novel approaches for altering lignin and even 'designing' the polymer to enhance its value or with a view toward its ...
Catherine Lapierre   +3 more
openaire   +5 more sources

Purification tags markedly affect self‐aggregation of CPEB3

open access: yesFEBS Letters, EarlyView.
Although recombinant proteins are used to study protein aggregation in vitro, uncleaved tags can interfere with accurate interpretation. Our findings demonstrate that His₆‐GFP and His₁₂ tags significantly affect liquid droplet and amyloid fibril formation in the intrinsically disordered region (IDR) of mouse cytoplasmic polyadenylation element‐binding ...
Harunobu Saito   +6 more
wiley   +1 more source

Materials and Structures Used in Aeronautics: Present and Future Perspectives [PDF]

open access: yesINCAS Bulletin
In recent years, significant advancements have been made in the development of novel materials for aeronautic applications. This effort aims to reduce costs by extending the operational life of structural and engine components, improving fuel economy ...
Mihai FLOREA   +5 more
doaj   +1 more source

Phenomenological rate-independent uniaxial hysteretic models: A mini-review

open access: yesFrontiers in Built Environment, 2022
A great variety of phenomenological models has been proposed over the years to model rate-independent hysteretic forces in structural mechanics. The classification of such models is usually based on the type of equation that needs to be solved to ...
Raffaele Capuano   +2 more
doaj   +1 more source

Circulating histones as clinical biomarkers in critically ill conditions

open access: yesFEBS Letters, EarlyView.
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez   +17 more
wiley   +1 more source

Contribution to probabilistic modeling of soil geo-mechanical properties for structural reliability analysis of buried pipes and foundations

open access: yesJournal of Materials and Engineering Structures, 2019
This present study synthesizes a numerical approach to optimize foundation systems design and underground pipes based on the combination of elastoplastic soil behavior and probabilistic modeling of its geo-mechanical characteristics.
Nabil KAZI TANI   +3 more
doaj  

Verrouillage professionnel

open access: yesRevue d'anthropologie des connaissances, 2014
Recent challenges such as sustainable development and climate change suggest engineers to focus on societal issues. However, as this case study of structural design shows, professional arrangements within the construction field constrain engineers ...
Andrew Chilvers, Sarah Bell
doaj   +1 more source

Structural Engineering for High‐Performance Flexible and Stretchable Strain Sensors

open access: yesAdvanced Intelligent Systems, 2021
Structural engineering is proved to be effective in improving both measurement sensitivity and range for flexible and stretchable strain sensors. Herein, the latest advancements in structural engineering strategies are summarized for the improvement of ...
Xin Huang, Zhouping Yin, Hao Wu
doaj   +1 more source

Insights into pegRNA design from editing of the cardiomyopathy‐associated phospholamban R14del mutation

open access: yesFEBS Letters, EarlyView.
This study reveals how prime editing guide RNA (pegRNA) secondary structure and reverse transcriptase template length affect prime editing efficiency in correcting the phospholamban R14del cardiomyopathy‐associated mutation. Insights support the design of structurally optimized enhanced pegRNAs for precise gene therapy.
Bing Yao   +7 more
wiley   +1 more source

Exchange requirement-based delivery method of structural design information for collaborative design using industry foundation classes

open access: yesJournal of Civil Engineering and Management, 2019
In Architecture, engineering, and construction (AEC) collaboration, exchange requirements (ERs) vary in different projects with different platforms. In order to ensure the completeness and accuracy of data sharing and exchange for structural engineering ...
Huahui Lai, Cheng Zhou, Xueyuan Deng
doaj   +1 more source

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