Results 41 to 50 of about 622,519 (292)

The anti‐CRISPR protein AcrIE8.1 inhibits the type I‐E CRISPR‐Cas system by directly binding to the Cascade subunit Cas11

FEBS Letters, EarlyView.
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley   +1 more source

Influence of coherent structure on turbulence characteristics of 0814 strong typhoon Hagupit

Shenzhen Daxue xuebao. Ligong ban, 2022
In order to explore the formation mechanism of the nonstationary wind speed in the eye wall regions and eye region of a typhoon, taking the measured data of No.0814 strong typhoon Hagupit as the research object, we identify and extract the coherent ...
LI Lixiao, HUANG Yuqing, CHEN Shangxin, HUANG Xigui, XIAO Yiqing, CHEN Xianchuan   +5 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Detection of Reinforced Concrete Blocks Using Two-Port Microwave CSRR Sensor

IEEE Access, 2022
In this paper, the design, fabrication and testing of a two-port transmission line-based microwave sensor for the detection of various structural concrete bricks is presented.
Mohammed M. Bait-Suwailam, Abdelazim M. Ahmed, Thamer S. Almoneef   +2 more
doaj   +1 more source

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

FEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang, Naoki Sunagawa, Toma Kashima, Kiyohiko Igarashi, Akimasa Miyanaga, Shinya Fushinobu   +5 more
wiley   +1 more source

The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity

FEBS Letters, EarlyView.
The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley   +1 more source

Enhancing Students’ Competency and Learning Experience in Structural Engineering through Collaborative Building Design Practices

Buildings, 2022
The field of the built environment is evolving, whereby the involvement of a multi-disciplinary team in the project becomes necessary. Complexities of issues keep challenging the industry of Architecture, Engineering and Construction (AEC) and address ...
Yani Rahmawati, Eugenius Pradipto, Zahiraniza Mustaffa, Ashar Saputra, Bashar Sami Mohammed, Christiono Utomo   +5 more
doaj   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

FEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Contribution to probabilistic modeling of soil geo-mechanical properties for structural reliability analysis of buried pipes and foundations

Journal of Materials and Engineering Structures, 2019
This present study synthesizes a numerical approach to optimize foundation systems design and underground pipes based on the combination of elastoplastic soil behavior and probabilistic modeling of its geo-mechanical characteristics.
Nabil KAZI TANI, Djamel NEDJAR, Tawfik TAMINE, Mabrouk HAMANE   +3 more
doaj  

Technical Specifications of Structural Health Monitoring for Highway Bridges: New Chinese Structural Health Monitoring Code

Frontiers in Built Environment, 2018
Governments and professional groups related to civil engineering write and publish standards and codes to protect the safety of critical infrastructure. In recent decades, countries have developed codes and standards for structural health monitoring (SHM)
Fernando Moreu, Fernando Moreu, Xiaomeng Li, Shunlong Li, Dongyu Zhang   +4 more
doaj   +1 more source