Results 41 to 50 of about 2,315,081 (285)
Structural Change in (Economic) Time Series [PDF]
, 2016 Methods for detecting structural changes, or change points, in time series data are widely used in many fields of science and engineering. This chapter sketches some basic methods for the analysis of structural changes in time series data. The exposition
A Aue +15 more
core +2 more sources
FEBS Letters, EarlyView.Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer +7 more
wiley +1 more source
Practical application of CFD for wind loading on tall buildings [PDF]
, 2009 This paper is concerned with assessing the scope of appicabiity for computational fluid dynamics(CFD) in the field of structural engineering, with a particular reference to tall buildings.
Bicanic, N. +4 more
core +2 more sources
FEBS Letters, EarlyView.Cells must clear mislocalized or faulty proteins from membranes to survive. The AAA+ ATPase Msp1 performs this task, but dissecting how its six subunits work together is challenging. We engineered linked dimers with varied numbers of functional subunits to reveal how Msp1 subunits cooperate and use energy to extract proteins from the lipid bilayer ...
Deepika Gaur +5 more
wiley +1 more source
Inverted pyramid Azores - an eternal hybrid structure
Structural Mechanics of Engineering Constructions and Buildings, 2021 Engineering structures are designed with observation of rules for structural performance under specific design loads, defined in the so-called structural codes. While dead loads are directly dependent from the selection of structural materials to a given
Luís Pedro F R Sarmento Esteves
doaj +1 more source
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Sensitivity Analysis of the Global Response of Flexible Rockfall Barriers
Geosciences, 2022 Protection barriers against the fall of boulders and rocks are structures with non-linear mechanical behaviour that make the study particularly complex.
Cyril Douthe +2 more
doaj +1 more source
The mathematical components of engineering expertise: the relationship between doing and understanding mathematics [PDF]
, 2002 this paper are extracts from our interviews with engineers.) Where, then, is the complex mathematics that certainly exists in modern engineering? Throughout all aspects of engineering design, computer software has an overwhelming presence.
Kent, Phillip, Noss, Richard
core +2 more sources
FEBS Letters, EarlyView.Phototrophs evolved light‐harvesting systems adapted for efficient photon capture in habitats enriched in far‐red radiation. A subset of eukaryotic pigment‐binding proteins can absorb far‐red photons via low‐energy chlorophyll states known as red forms.
Antonello Amelii +8 more
wiley +1 more source
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source