Results 41 to 50 of about 2,389,484 (283)

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Boosting Ambient Hydrogen Storage in Graphene via Structural and Functional Designs: A Review

open access: yesAdvanced Energy & Sustainability Research
Graphene with a large specific surface area, excellent mechanical flexibility, and chemical adjustability is a promising medium for reversible hydrogen storage.
Shun Wang, Chaojie Liu, Yongyang Zhu
doaj   +1 more source

Materials and Structures Used in Aeronautics: Present and Future Perspectives [PDF]

open access: yesINCAS Bulletin
In recent years, significant advancements have been made in the development of novel materials for aeronautic applications. This effort aims to reduce costs by extending the operational life of structural and engine components, improving fuel economy ...
Mihai FLOREA   +5 more
doaj   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

open access: yesFEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Artificial Intelligence-Based Design and Analysis of Passive Control Structures: An Overview [PDF]

open access: yesJournal of Soft Computing in Civil Engineering
Recently, artificial intelligence (AI) has been widely adopted in the design and analysis of passively controlled structures. This study provides a comprehensive overview of AI-based methodologies aimed at enhancing the resilience and efficiency of ...
Ausamah AL Houri   +2 more
doaj   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Discrete Sizing Optimization of Steel Structures Using Modified Fireworks Algorithm [PDF]

open access: yesJournal of Soft Computing in Civil Engineering
Fireworks algorithm (FWA) is an artificial intelligence algorithm developed by emulating the burst process of fireworks. This paper applies a modified version of fireworks algorithm called MoFWA to design disparate steel trusses and planar frames.
Navid Seraji, Mehdi Babaei
doaj   +1 more source

Influence of coherent structure on turbulence characteristics of 0814 strong typhoon Hagupit

open access: yesShenzhen Daxue xuebao. Ligong ban, 2022
In order to explore the formation mechanism of the nonstationary wind speed in the eye wall regions and eye region of a typhoon, taking the measured data of No.0814 strong typhoon Hagupit as the research object, we identify and extract the coherent ...
LI Lixiao   +5 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Contribution to probabilistic modeling of soil geo-mechanical properties for structural reliability analysis of buried pipes and foundations

open access: yesJournal of Materials and Engineering Structures, 2019
This present study synthesizes a numerical approach to optimize foundation systems design and underground pipes based on the combination of elastoplastic soil behavior and probabilistic modeling of its geo-mechanical characteristics.
Nabil KAZI TANI   +3 more
doaj  

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