Results 61 to 70 of about 1,885,843 (350)
Background: One of the new methods of scaffold fabrication is a nano-micro hybrid structure in which the properties of the scaffold are improved by introducing nanometer and micrometer structures.
Saeed Karbasi+4 more
semanticscholar +1 more source
ECNet is an evolutionary context-integrated deep learning framework for protein engineering
Machine learning has been increasingly used for protein engineering. However, because the general sequence contexts they capture are not specific to the protein being engineered, the accuracy of existing machine learning algorithms is rather limited ...
Yunan Luo+9 more
semanticscholar +1 more source
Evolutionary interplay between viruses and R‐loops
Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi+4 more
wiley +1 more source
Mal-Netminer: Malware Classification Approach based on Social Network Analysis of System Call Graph [PDF]
As the security landscape evolves over time, where thousands of species of malicious codes are seen every day, antivirus vendors strive to detect and classify malware families for efficient and effective responses against malware campaigns.
Jang, Jae-wook+4 more
core +3 more sources
Purification tags markedly affect self‐aggregation of CPEB3
Although recombinant proteins are used to study protein aggregation in vitro, uncleaved tags can interfere with accurate interpretation. Our findings demonstrate that His₆‐GFP and His₁₂ tags significantly affect liquid droplet and amyloid fibril formation in the intrinsically disordered region (IDR) of mouse cytoplasmic polyadenylation element‐binding ...
Harunobu Saito+6 more
wiley +1 more source
Engineering design has traditionally involved human engineers manually creating and iterating on designs based on their expertise and knowledge. In Bio-inspired Evolutionary Development (EvoDevo), generative algorithms are used to ex-plore a much larger design space that may not have ever been considered by human engineers. However, for complex systems,
Buchanan, Edgar+6 more
openaire +2 more sources
Circulating histones as clinical biomarkers in critically ill conditions
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez+17 more
wiley +1 more source
Bannan Engineering Laboratories Redesign [PDF]
Due to the growing student body within Santa Clara University\u27s School of Engineering, an increase in classrooms, laboratories, offices, and study spaces is needed to for student engineering resources.
Candelaria, Pia Johanna+2 more
core +1 more source
Proton translocation in proteins [PDF]
The active transport of protons across the low dielectric barrier imposed by biological membranes is accomplished by a plethora of proteins that span the ca. 40 Å of the phospholipid bilayer.
Chan, Sunney I., Copeland, Robert A.
core +1 more source
Cancer‐associated fibroblasts (CAFs) promote cancer growth, invasion (metastasis), and drug resistance. Here, we identified functional and diverse circulating CAFs (cCAFs) in patients with metastatic prostate cancer (mPCa). cCAFs were found in higher numbers and were functional and diverse in mPCa patients versus healthy individuals, suggesting their ...
Richell Booijink+6 more
wiley +1 more source