Results 61 to 70 of about 1,612,198 (310)

Hyaluronan hydration generates three-dimensional meso-scale structure in engineered collagen tissues [PDF]

Journal of The Royal Society Interface, 2012
Here, we show that the local incorporation of osmotically active hyaluronan into previously compressed collagen constructs results in further rapid dehydration/compression of collagen layers, channel formation and generation of new interfaces; these novel structures, at the nano–micro (i.e.
Nelomi, Anandagoda, Daniel G, Ezra, Umber, Cheema, Maryse, Bailly, Robert A, Brown   +4 more
openaire   +2 more sources

Assessment of First-Principles and Semiempirical Methodologies for Absorption and Emission Energies of Ce$^{3+}$-Doped Luminescent Materials

, 2017
In search of a reliable methodology for the prediction of light absorption and emission of Ce$^{3+}$-doped luminescent materials, 13 representative materials are studied with first-principles and semiempirical approaches. In the first-principles approach,
Gonze, Xavier, Jia, Yongchao, Miglio, Anna, Mikami, Masayoshi, Poncé, Samuel   +4 more
core   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source

Data-Driven Exploration of Sc-Induced mechanical enhancement in Al-Cu-Li alloys

Materials & Design
A data-driven strategy was developed to identify microalloying elements that simultaneously enhance the yield strength, elongation, and elastic modulus of Al-Cu-Li alloys. Among 71 T6-tempered compositions, Sc was identified as the most promising element
Lyu Jing, Li Yanan, Li Xiwu, Zheng Lei, Li Changlin, Xiao Wei, Wen Kai, Li Ying   +7 more
doaj   +1 more source

Shear critical R/C columns under increasing axial load [PDF]

, 2020
Structural elements in old reinforced concrete (R/C) frame buildings are often prone to shear or flexure-shear failure, which can eventually lead to loss of axial load capacity of vertical elements and initiate vertical progressive collapse of a building.
Elwood, Ghannoum, Ghannoum, Izzuddin, Lew, Lynn, Murray, Ousalem, Sasani, Sezen, Sezen, Xu, Yu, Zimos, Zimos   +14 more
core   +2 more sources

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

A new finite element for generalized in-plane pipe loading. Experimental and numerical comparison [PDF]

, 2010
In structural engineering, the geometry of a large number of structural details may involve the combination of straight and curved parts in order to meet requirements of functionality and/or attractive design.
Fonseca, E.M.M., Melo, F.J.M.Q. de, Oliveira, C.A.M de, Piloto, P.A.G.   +3 more
core  

Review of the Synergies Between Computational Modeling and Experimental Characterization of Materials Across Length Scales

, 2015
With the increasing interplay between experimental and computational approaches at multiple length scales, new research directions are emerging in materials science and computational mechanics.
Dingreville, Rémi, Karnesky, Richard A., Puel, Guillaume, Schmitt, Jean-Hubert   +3 more
core   +3 more sources

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

Uncertainty Propagation and Feature Selection for Loss Estimation in Performance-based Earthquake Engineering [PDF]

, 2004
This report presents a new methodology, called moment matching, of propagating the uncertainties in estimating repair costs of a building due to future earthquake excitation, which is required, for example, when assessing a design in performance-based ...
Beck, James L., Ching, Jianye, Porter, Keith A.   +2 more
core