Results 61 to 70 of about 1,885,843 (350)

Evaluation of structural and mechanical properties of electrospun nano-micro hybrid of poly hydroxybutyrate-chitosan/silk scaffold for cartilage tissue engineering

open access: yesAdvanced Biomedical Research, 2016
Background: One of the new methods of scaffold fabrication is a nano-micro hybrid structure in which the properties of the scaffold are improved by introducing nanometer and micrometer structures.
Saeed Karbasi   +4 more
semanticscholar   +1 more source

ECNet is an evolutionary context-integrated deep learning framework for protein engineering

open access: yesNature Communications, 2021
Machine learning has been increasingly used for protein engineering. However, because the general sequence contexts they capture are not specific to the protein being engineered, the accuracy of existing machine learning algorithms is rather limited ...
Yunan Luo   +9 more
semanticscholar   +1 more source

Evolutionary interplay between viruses and R‐loops

open access: yesFEBS Letters, EarlyView.
Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi   +4 more
wiley   +1 more source

Mal-Netminer: Malware Classification Approach based on Social Network Analysis of System Call Graph [PDF]

open access: yes, 2015
As the security landscape evolves over time, where thousands of species of malicious codes are seen every day, antivirus vendors strive to detect and classify malware families for efficient and effective responses against malware campaigns.
Jang, Jae-wook   +4 more
core   +3 more sources

Purification tags markedly affect self‐aggregation of CPEB3

open access: yesFEBS Letters, EarlyView.
Although recombinant proteins are used to study protein aggregation in vitro, uncleaved tags can interfere with accurate interpretation. Our findings demonstrate that His₆‐GFP and His₁₂ tags significantly affect liquid droplet and amyloid fibril formation in the intrinsically disordered region (IDR) of mouse cytoplasmic polyadenylation element‐binding ...
Harunobu Saito   +6 more
wiley   +1 more source

Investigation of starting conditions in generative processes for the design of engineering structures

open access: yes2023 IEEE Symposium Series on Computational Intelligence (SSCI), 2023
Engineering design has traditionally involved human engineers manually creating and iterating on designs based on their expertise and knowledge. In Bio-inspired Evolutionary Development (EvoDevo), generative algorithms are used to ex-plore a much larger design space that may not have ever been considered by human engineers. However, for complex systems,
Buchanan, Edgar   +6 more
openaire   +2 more sources

Circulating histones as clinical biomarkers in critically ill conditions

open access: yesFEBS Letters, EarlyView.
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez   +17 more
wiley   +1 more source

Bannan Engineering Laboratories Redesign [PDF]

open access: yes, 2014
Due to the growing student body within Santa Clara University\u27s School of Engineering, an increase in classrooms, laboratories, offices, and study spaces is needed to for student engineering resources.
Candelaria, Pia Johanna   +2 more
core   +1 more source

Proton translocation in proteins [PDF]

open access: yes, 1989
The active transport of protons across the low dielectric barrier imposed by biological membranes is accomplished by a plethora of proteins that span the ca. 40 Å of the phospholipid bilayer.
Chan, Sunney I., Copeland, Robert A.
core   +1 more source

Identification of functional and diverse circulating cancer‐associated fibroblasts in metastatic castration‐naïve prostate cancer patients

open access: yesMolecular Oncology, Volume 19, Issue 7, Page 2074-2091, July 2025.
Cancer‐associated fibroblasts (CAFs) promote cancer growth, invasion (metastasis), and drug resistance. Here, we identified functional and diverse circulating CAFs (cCAFs) in patients with metastatic prostate cancer (mPCa). cCAFs were found in higher numbers and were functional and diverse in mPCa patients versus healthy individuals, suggesting their ...
Richell Booijink   +6 more
wiley   +1 more source

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