Results 101 to 110 of about 26,686 (263)

Seismic behavior and assessment of masonry heritage structures. Needs in engineering judgement and education

open access: yesRILEM Technical Letters, 2019
Built cultural heritage is at risk due to manmade and natural hazards. The seismic vulnerability of ancient masonry buildings is particularly difficult to assess and requires specialized technical skills.
Paulo Lourenco, Georgios Karanikoloudis
doaj   +1 more source

ATP13A2 is involved in intracellular polyamine transport in lung epithelial cells

open access: yesFEBS Open Bio, EarlyView.
Spermidine transport in lung epithelial cells involves the polyamine transporter ATP13A2. Cell proliferation is associated with the upregulation of ATP13A2. Polyamines are present in all living cells and are implicated in various crucial cellular processes such as proliferation, apoptosis and autophagy.
Yuta Hatori   +8 more
wiley   +1 more source

TMC4 localizes to multiple taste cell types in the mouse taste papillae

open access: yesFEBS Open Bio, EarlyView.
Transmembrane channel‐like 4 (TMC4), a voltage‐dependent chloride channel, plays a critical role in amiloride‐insensitive salty taste transduction. TMC4 is broadly expressed in all mature taste cell types, suggesting a possible involvement of multiple cell types in this pathway.
Momo Murata   +6 more
wiley   +1 more source

FINDING THE STRAIN –STRESS STATE OF ENGINEERING BUILDINGS. OPTIMIZATION OF STRUCTURAL SOLUTIONS

open access: yesNauka ta progres transportu, 2010
Industrial pipes are an integral part of the complex structures of enterprises of metallurgical, chemical and other industries from the moment of their advent. Their purpose is to exhaust industrial wastes with residual content of hazardous substances on
V. Ye. Volkova, M. S. Oleynik
doaj  

Historical background, current trends and future prospects of supertall buildings

open access: yesDiscover Civil Engineering
Skyscrapers having a height of 300 m or more, but less than 600 m, are designated as supertall buildings. The first supertall building was constructed in New York City in the year 1930.
Tanmoy Konar
doaj   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

open access: yesFEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu   +5 more
wiley   +1 more source

DISCUSSION. ECONOMICS OF MULTI-STOREY BUILDINGS. STRUCTURAL AND BUILDING ENGINEERING DIVISION. [PDF]

open access: yesThe Institution of Civil Engineers Engineering Division Papers, 1945
G P MANNING   +9 more
openaire   +1 more source

A method of building information modelling implementation for structural engineering firms

open access: yesMethodsX
Building Information Modelling (BIM), a new concept and methodology, has received much attention lately. Various Structural Engineering Firms (SEFs) have observed substantial competitive benefits after its deployment. BIM offers a wide range of advantages, but its capacity has not even been completely exploited. The challenges of firm implementation, a
Ibrahim F. Varouqa, Moawiah A. Alnsour
openaire   +3 more sources

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

open access: yesFEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava   +3 more
wiley   +1 more source

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