Results 81 to 90 of about 26,686 (263)

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

Evolution of Persian traditional architecture through the history

Journal of Architecture and Urbanism, 2015
The architecture of Iran is wholly based on the comprehensive use of knowledge of both metaphysical and physical sciences. Architecture and structural engineering in Iran involve a great range of buildings distributed over a vast area from the borders of
Mehrdad Hejazi, Bina Hejazi, Saba Hejazi
doaj   +1 more source

Issues of contemporary wind engineering and aerodynamics of building structures

Budownictwo i Architektura, 2016
The paper reviews nowadays problems and issues of wind engineering and aerodynamics of building structures. The article mainly focuses on aerodynamics of building structures, shortly characterizing theoretical bases, which one must take into account when assuming wind loads.
Tomasz Lipecki, Paulina Jamińska
openaire   +3 more sources

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source

Damage observations of RC buildings from 2023 Kahramanmaraş earthquake sequence and discussion on the seismic code regulations

Bulletin of Earthquake Engineering
Kahramanmaraş Earthquake Sequence of 6th of February is the deadliest earthquake that happened in Turkey in the era of instrumental seismology, claiming more than 55 thousand lives and leaving torn down cities and towns behind.
E. Vuran, Cavit Serhatoğlu, M. Timurağaoğlu, E. Smyrou, İ. Bal, R. Livaoğlu   +5 more
semanticscholar   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Application of finite element analysis in the formal analysis of ancient architectural plaque section

Nonlinear Engineering
Ancient architecture in Tibet has attracted considerable research attention because of its historical, religious, and artistic significance. Because the design and construction of ancient buildings often do not have the same detailed documentation as ...
Su Wen, Hua Yixiong
doaj   +1 more source

CFD Simulation of the Interference Effects of Wind Pressures in Building Groups

MATEC Web of Conferences, 2018
The effect of interference is a hot topic in structural wind engineering. In order to investigate the phenomena of this effect, some cases, including single interfered building, double interfered buildings and building matrixes, were simulated by the ...
Sun Yi, Wang Mei, Liu Bowei
doaj   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Finding the strain –stress state of engineering buildings. Optimization of structural solutions

Science and Transport Progress, 2011
Industrial pipes are an integral part of the complex structures of enterprises of metallurgical, chemical and other industries from the moment of their advent. Their purpose is to exhaust industrial wastes with residual content of hazardous substances on a considerable height.
Volkova, V. Ye., Oleynik, M. S.
openaire   +3 more sources