Results 131 to 140 of about 813,020 (358)
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
How Does Sub-National Autonomy Affect the Effectiveness of Structural Funds? [PDF]
Economic and social cohesion between the EU Member States is one of the explicitly stated goals in the Treaty on European Union. The EU’s Structural Funds as a part of the Union’s regional policies are a mechanism of conditional grants that provides co ...
Cornelius Baehr
core
Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini +2 more
wiley +1 more source
Fertile soil for Structural Funds? A panel data analysis of the conditional effectiveness of European cohesion policy Author-Name: Sjef Ederveen [PDF]
Structural funds are the most intensively used policy instrument by the European Union to promote economic growth in its member states and to speed up the process of convergence.
Henri L.F. De Groot, Richard Nahuis
core
Going NUTS: The Effect of EU Structural Funds on Regional Performance
Sascha O. Becker +3 more
openalex +2 more sources
DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling
Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang +7 more
wiley +1 more source
Effectiveness of structural funds – microlevel perspective (case of Slovakia) [PDF]
Cohesion policy and regional policy as a main part of cohesion policy are the most important policies of European Union. This could also be view from the volume of financial resources allocated for these policies.
Miroslav Å ipikal
core
KHS‐Cnd peptide is able to impair biofilm formation and disaggregate mature biofilms in Acinetobacter baumannii clinical isolates. Differences in extracellular metabolites reflect changes in biofilm metabolism due to KHS‐Cnd treatment. Among the differentially represented extracellular metabolites upon KHS‐Cnd treatment, the significantly altered ...
Fernando Porcelli +9 more
wiley +1 more source

