Results 51 to 60 of about 813,020 (358)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Mutual Fund Capital Structure

open access: yesSSRN Electronic Journal, 2017
The Investment Company Act of 1940 regulates the capital structure of mutual funds in order to restrain their leverage and speculative character. It is often (mistakenly) assumed that the law prohibits open-end mutual funds from borrowing money. This Article (i) analyzes the law governing mutual fund capital structure to reveal when (and to what extent)
openaire   +2 more sources

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

Quality of project financed by the European Union structural funds

open access: yesMATEC Web of Conferences, 2018
The European Union structural funds even out the chances of development of particular regions in the European Union. Entities applying for additional financing from structural funds for various actions implemented in a form of projects must meet specific
Kozień Ewa
doaj   +1 more source

STRUCTURAL FUNDS AND OVERCOMING THE ECONOMIC CRISIS Emilian M. Dobrescu, Romanian Academy and Spiru Haret University Cristina Barna, Spiru Haret University Bucharest [PDF]

open access: yes
The European Commission is the authority that supervises the EuropeanUnion structural funds, which are meant to finance the measures of structural aid at thecommunity level, aiming to promote the regions lagging behind in development, toreconvert the ...
Cristina Barna, Emilian M. Dobrescu
core  

On the road to regional ‘Competitive Environmental Sustainability’: the role of the European structural funds [PDF]

open access: hybrid, 2023
Anabela Santos   +4 more
openalex   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

The Impact of Structural Funds Policy on European Regions' Growth : A Theoretical and Empirical Approach [PDF]

open access: yes
In this paper, I try to estimate the impact of Structural Funds on the growth rates of Objective 1 European regions during the two first programming periods (1989-2000). I develop a "hybrid" model of economic growth that partially endogenizes the rate of
Mari Carmen Puigcerver-Penalver
core   +3 more sources

How does Institutional Setting Affect the Impact of EU Structural Funds on Economic Cohesion? New Evidence from Central and Eastern Europe [PDF]

open access: yes
Structural Funds are the main instrument of the EU cohesion policy. Their effective use is subject to an ongoing debate in political and scientific circles.
Marina Grusevaja, Toralf Pusch
core  

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