Results 51 to 60 of about 809,383 (310)
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
The Use Of EU Structural Funds By Enterprises In The Lodz Region
Comparative Economic Research, 2013 The issue of how to stimulate economic growth and development remains an open question. The EU structural funds are meant to help solve the problem at the regional level within the framework of the cohesion policy.
Tomasz Dorożyński +2 more
doaj +1 more source
SSRN Electronic Journal, 2017 The Investment Company Act of 1940 regulates the capital structure of mutual funds in order to restrain their leverage and speculative character. It is often (mistakenly) assumed that the law prohibits open-end mutual funds from borrowing money. This Article (i) analyzes the law governing mutual fund capital structure to reveal when (and to what extent)
openaire +2 more sources
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Quality of project financed by the European Union structural funds
MATEC Web of Conferences, 2018 The European Union structural funds even out the chances of development of particular regions in the European Union. Entities applying for additional financing from structural funds for various actions implemented in a form of projects must meet specific
Kozień Ewa
doaj +1 more source
How does Institutional Setting Affect the Impact of EU Structural Funds on Economic Cohesion? New Evidence from Central and Eastern Europe [PDF]
Structural Funds are the main instrument of the EU cohesion policy. Their effective use is subject to an ongoing debate in political and scientific circles.
Marina Grusevaja, Toralf Pusch
core
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
EU Development Policies and the Socio-Economic Disadvantage of European Regions. [PDF]
The debate over the EU budget 2007-2013 made clear the need of an in-depth understanding of the distribution of the EU development funds. The scarce resources available need to be targeted more effectively towards the real needs of EU countries and ...
Riccardo Crescenzi
core
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source