Results 81 to 90 of about 563,295 (265)
Vibration fatigue comparative test and life prediction for titanium alloy connection structures
Hangkong gongcheng jinzhanA large number of mechanical connection structures in aircraft face vibration fatigue problems，and the evaluation of vibration fatigue performance is the key to determine the service life，safety design and evaluation of the structure.
HE Shi +4 more
doaj +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Hangkong gongcheng jinzhanCircuit parameters are the decisive factors for the heating performance of graphite heating elements，and the research on the influence of circuit parameters is the basis for the design of high-performance and high-reliability graphite heaters.
LI Junpeng +4 more
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
A home for integrative structural models [PDF]
Nature Methods, 2018 PDB-Dev hosts integrative structural models of biomolecular assemblies solved by hybrid methods.
openaire +2 more sources
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
The module structure of integral designs
Journal of Combinatorial Theory, Series A, 1973 AbstractThe existence problem for t-designs with prescribed parameters is solved by allowing positive and negative integral multiplicities for the blocks.
Jack E. Graver, W. B. Jurkat
openaire +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Random Vibration Fatigue Life Analysis of Aeroengine Bolts Using the Frequency-Domain Method
Fatigue of Aircraft StructuresBolt connections are widely used in aircraft engines due to their advantages of high stiffness, low weight, and ease of assembly and disassembly. However, they are subjected to complex stress states in service, including high preloads, combustion-induced
Tian Lilin +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source