Results 81 to 90 of about 623,007 (310)

Structural integrity assessment of superheater outlet penetration tubeplate

open access: yes, 2009
In recent years, the Linear Matching Method (LMM) has been well developed for the integrity assessment of the component subjected to cyclic thermal and mechanical loads.
Haofeng Chen   +3 more
core   +1 more source

Roles for DNA polymerase δ in initiating and terminating leading strand DNA replication

open access: yesNature Communications, 2019
DNA polymerases epsilon and delta, respectively, perform the majority of leading and lagging strand replication of the eukaryotic nuclear genome. Here the authors map the ribonucleotide fingerprints of the polymerases to show the special roles of ...
Zhi-Xiong Zhou   +4 more
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

A role for the stringent response in ciprofloxacin resistance in Pseudomonas aeruginosa

open access: yesScientific Reports
Pseudomonas aeruginosa is a major cause of nosocomial infections and the leading cause of chronic lung infections in cystic fibrosis and chronic obstructive pulmonary disease patients. Antibiotic treatment remains challenging because P.
Libertad García-Villada   +4 more
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Integrated structural analysis tool using linear matching method part 1 : Software development

open access: yes, 2014
A number of direct methods based upon the Linear Matching Method (LMM) framework have been developed to address structural integrity issues for components subjected to cyclic thermal and mechanical load conditions.
Tipping, David   +2 more
core   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Merging nano and macro structure design: opportunities for the structural integrity of steel infrastructure

open access: yes
Merging the macro-level design with the nano-level design in structural engineering, hence, using the superior properties of nanostructured metallic multilayers for protecting fatigue-critical joints of the macrostructure and ensuring the structural ...
Seidelmann, Maren   +4 more
core   +1 more source

Integrity of sub-structural systems during earthquake: indian and international perspectives.

open access: yes, 2010
Structural integrity of underground constructions or sub-structures like foundations, anchors, basements, piles, piers, abutments, retaining walls, subgrade of railway, highway, airport runway etc.
Choudhury, Deepankar
core   +1 more source

An essential role of KREPB4 in RNA editing and structural integrity of the editosome in Trypanosoma brucei [PDF]

open access: yes, 2007
RNA editing in the sleeping sickness parasite Trypanosoma brucei remodels mitochondrial transcripts by the addition and deletion of uridylates as specified by guide RNAs.
Schnaufer, Achim; id_orcid   +4 more
core   +1 more source

Home - About - Disclaimer - Privacy