Results 71 to 80 of about 623,007 (310)
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
593600Proton Exchange Membrane Fuel Cells (PEMFC) are widely assumed as a clean alternative energy source to fossil fuels, being expected to be a growing field in the future.
Kuwatsch, Thomas +11 more
core +1 more source
Process Parameter Optimisation in Laser Powder Bed Fusion of Duplex Stainless Steel 2205
Applied SciencesAdditive Manufacturing (AM) appears as a very interesting alternative to conventional production routes for alloys and metals, thanks to the fact that at the end of printing, the final product is obtained directly.
N. Mayoral +5 more
doaj +1 more source
Electron transfer between complexes III and IV in S. cerevisiae mitochondrial membranes
FEBS Letters, EarlyView.Mitochondrial oxidative phosphorylation in S. cerevisiae mitoplasts is limited by complex IV catalytic capacity, rather than two‐dimensional cytochrome c diffusion. At physiological cytochrome c : supercomplex ratios at salinity equivalent to that of 20 mm monovalent salt, activity is maximized, indicating that this low ionic strength accurately mimics
Ana Paula Lobez +2 more
wiley +1 more source
Structural integrity assessment of an offshore platform using RB-FEA
The wind energy is considered as one of feasible renewable energy sources especially in the offshore field to speed up the green transition. However, the cost related to the design and the installation on a new structure its structural management still ...
Raimondo Luciano +3 more
core +2 more sources
Failure Analysis of Large-Scale Composite Fuselage Panels Under Combined Loads
AerospaceThe fuselage serves as the primary component of commercial aircraft. The strength reliability of fuselage panels is therefore crucial for commercial aircraft.
Fei Yuan +5 more
doaj +1 more source
Phosphoinositides and inositol phosphates as molecular glues
FEBS Letters, EarlyView.Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source
Experimental and simulation study on explosion impact of a typical wall panel structure
Hangkong gongcheng jinzhanThe damage effect of the explosion shock wave generated by the explosion of the air to air missile warhead on the aircraft skin structure is influenced by various factors，and the function mechanism is relatively com plex，so that a large number of ...
ZHOU Jiayu +5 more
doaj +1 more source
FEBS Letters, EarlyView.Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara +3 more
wiley +1 more source