Results 101 to 110 of about 1,140,542 (305)

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

open access: yesFEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth   +6 more
wiley   +1 more source

Industrial-grade carbon fiber reinforced epoxy vitrimer composites: Reprocessing, repairing and recycling

open access: yesAdvanced Industrial and Engineering Polymer Research
Carbon fiber reinforced thermoset composites (CFRP) have demonstrated significant potential for industrial applications. However, their permanent cross-linked networks pose challenges for reprocessing, repairing, and recycling.
Mei Fang   +6 more
doaj   +1 more source

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

open access: yesFEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman   +4 more
wiley   +1 more source

The energy absorption capacity of a novel dual-sub-fold Miura foldcore subjected to axial crushing

open access: yesMaterials & Design
A modified Miura foldcore geometry was developed by introducing sub-folds into the cell walls of a conventional Miura foldcore. Similar to other sub-fold Miura foldcores, stable plastic hinge lines were generated at sub-fold sites under the guidance of ...
Caihua Zhou   +4 more
doaj   +1 more source

Block-Coordinate Frank-Wolfe Optimization for Structural SVMs

open access: yes, 2013
We propose a randomized block-coordinate variant of the classic Frank-Wolfe algorithm for convex optimization with block-separable constraints. Despite its lower iteration cost, we show that it achieves a similar convergence rate in duality gap as the ...
Jaggi, Martin   +3 more
core   +3 more sources

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

open access: yesFEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake   +4 more
wiley   +1 more source

Structural optimization of large structural systems by optimality criteria methods [PDF]

open access: yes
The fundamental concepts of the optimality criteria method of structural optimization are presented. The effect of the separability properties of the objective and constraint functions on the optimality criteria expressions is emphasized.
Berke, Laszlo
core   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

Experiment research on damage effect of underwater multipoint synchronous explosion on semi-cylindrical shell

open access: yesApplied Ocean Research
This study uses experimental methods to investigate the damage characteristics of typical underwater structures under synchronous array charge underwater explosions. Small-scale underwater explosion tests are conducted in a water tank to study the damage
Zhifan Zhang   +4 more
doaj   +1 more source

Payload shrouds structural optimization study Final report [PDF]

open access: yes
Computer programs for synthesizing structural arrangements for ring-stiffened, honeycomb sandwich, and ring-stringer stiffened methods of construction for Saturn nose ...
Hendrix, E. S.
core   +1 more source

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