Results 101 to 110 of about 1,128,803 (283)
Applied Ocean ResearchThis study uses experimental methods to investigate the damage characteristics of typical underwater structures under synchronous array charge underwater explosions. Small-scale underwater explosion tests are conducted in a water tank to study the damage
Zhifan Zhang +4 more
doaj +1 more source
Structural optimization of large structural systems by optimality criteria methods [PDF]
The fundamental concepts of the optimality criteria method of structural optimization are presented. The effect of the separability properties of the objective and constraint functions on the optimality criteria expressions is emphasized.
Berke, Laszlo
core +1 more source
Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
Molecular Oncology, EarlyView.PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
The energy absorption capacity of a novel dual-sub-fold Miura foldcore subjected to axial crushing
Materials & DesignA modified Miura foldcore geometry was developed by introducing sub-folds into the cell walls of a conventional Miura foldcore. Similar to other sub-fold Miura foldcores, stable plastic hinge lines were generated at sub-fold sites under the guidance of ...
Caihua Zhou +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics
FEBS Open Bio, EarlyView.Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini +2 more
wiley +1 more source
Optimization of fiber reinforced structures to satisfy aeroelastic requirements [PDF]
A numerical procedure was developed for minimizing the structural mass of an aircraft structure which must have a specified minimum flutter velocity or divergence velocity. During the optimization process the arrangement of the structural members remains
Rudisill, C. S.
core +1 more source
SmallTalk: a novel small‐sized fusion tag for peptide expression and purification
FEBS Open Bio, EarlyView.The SmallTalk fusion tag allows for the efficient expression and purification of soluble recombinant proteins or peptides in Escherichia coli. Testing with SmallTalk‐GFP confirmed that the proteins were soluble and folded correctly, while SmallTalk‐Bin1b maintained its antimicrobial activity against various bacterial isolates. This streamlined workflow
Atika Tariq +3 more
wiley +1 more source
EnergiesAirborne Wind Energy (AWE) systems offer benefits such as high altitude access to stronger and more stable winds, reduced environmental impact, and cost effective infrastructure.
Yanjun Lv +4 more
doaj +1 more source