Results 51 to 60 of about 1,128,803 (283)

Microscopic stress-constrained two-scale topology optimisation for additive manufacturing

Virtual and Physical Prototyping
The extraordinary mechanical properties of additive manufactured two-scale lattice structures can be substantially enhanced by employing optimisation techniques at both macroscopic and microscopic scales.
Xiaopeng Zhang, Zheng Ni, Akihiro Takezawa, Yaguang Wang, Zhan Kang   +4 more
doaj   +1 more source

Optimal Respiratory Controller Structures

IEEE Transactions on Biomedical Engineering, 1986
It has been assumed that there exists an explicit "exercise stimulus" (i. e., a signal that is correlated to metabolic CO2 production and appropriately drives breathing). Alternatively, the behavior of the respiratory controller during exercise and inspiratory CO2 loading may be dictated by an optimal controller. The purpose of this paper is to examine
Swanson, G, Robbins, P
openaire   +2 more sources

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

The analytical model of crimping springback for large-diameter longitudinal welded pipe

Journal of Engineering and Applied Science
The crimping technique is widely used in the manufacturing process of large-diameter longitudinal welded pipe. In the bending process, the springback is the critical problem affecting the shape, which is the key index of forming quality.
Ji Zhang, Kai Sun
doaj   +1 more source

Coupling strengthening mechanism of precipitate and solute atoms in edge dislocation motion of Al-Mg-Si alloy

Journal of Materials Research and Technology
To investigate the coupling strengthening mechanism of precipitate and Cu solute atoms in Al-Mg-Si alloy, the molecular dynamics model of edge dislocation motion interacted with precipitate and Cu solute atoms was established.
Shining Kong, Zelong Yu, Xinyu Zhang, Zhao Zhang   +3 more
doaj   +1 more source

Optimization of sharp and viewing-angle-independent structural color [PDF]

, 2015
Structural coloration produces some of the most brilliant colors in nature and has many applications. However, the two competing properties of narrow bandwidth and broad viewing angle have not been achieved simultaneously in previous studies.
Hsu, Chia Wei, Johnson, Steven G., Miller, Owen D., Soljačić, Marin   +3 more
core   +2 more sources

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Inverse design of mechanical metamaterial achieving a prescribed constitutive curve

Theoretical and Applied Mechanics Letters
Besides exhibiting excellent capabilities such as energy absorption, phase-transforming metamaterials offer a vast design space for achieving nonlinear constitutive relations. This is facilitated by switching between different patterns under deformation.
Zongliang Du, Tanghuai Bian, Xiaoqiang Ren, Yibo Jia, Shan Tang, Tianchen Cui, Xu Guo   +6 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source