Results 51 to 60 of about 1,140,542 (305)
Learning-based ship design optimization approach [PDF]
, 2012 With the development of computer applications in ship design, optimization, as a powerful approach, has been widely used in the design and analysis process.
Cui, Hao, Sayer, Philip, Turan, Osman
core +1 more source
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Microscopic stress-constrained two-scale topology optimisation for additive manufacturing
Virtual and Physical PrototypingThe extraordinary mechanical properties of additive manufactured two-scale lattice structures can be substantially enhanced by employing optimisation techniques at both macroscopic and microscopic scales.
Xiaopeng Zhang +4 more
doaj +1 more source
Optimal Respiratory Controller Structures
IEEE Transactions on Biomedical Engineering, 1986 It has been assumed that there exists an explicit "exercise stimulus" (i. e., a signal that is correlated to metabolic CO2 production and appropriately drives breathing). Alternatively, the behavior of the respiratory controller during exercise and inspiratory CO2 loading may be dictated by an optimal controller. The purpose of this paper is to examine
Swanson, G, Robbins, P
openaire +2 more sources
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Journal of Materials Research and TechnologyTo investigate the coupling strengthening mechanism of precipitate and Cu solute atoms in Al-Mg-Si alloy, the molecular dynamics model of edge dislocation motion interacted with precipitate and Cu solute atoms was established.
Shining Kong +3 more
doaj +1 more source
Cluster-Based Optimization of Cellular Materials and Structures for Crashworthiness [PDF]
, 2018 The objective of this work is to establish a cluster-based optimization method for the optimal design of cellular materials and structures for crashworthiness, which involves the use of nonlinear, dynamic finite element models. The proposed method uses a
Detwiler, Duane, Liu, Kai, Tovar, Andres
core +1 more source
Molecular Oncology, EarlyView.Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié +13 more
wiley +1 more source
The analytical model of crimping springback for large-diameter longitudinal welded pipe
Journal of Engineering and Applied ScienceThe crimping technique is widely used in the manufacturing process of large-diameter longitudinal welded pipe. In the bending process, the springback is the critical problem affecting the shape, which is the key index of forming quality.
Ji Zhang, Kai Sun
doaj +1 more source
Molecular Oncology, EarlyView.This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris +10 more
wiley +1 more source