Results 211 to 220 of about 4,111,769 (301)

insilicoSV: a flexible grammar-based framework for structural variant simulation and placement. [PDF]

Bioinformatics
Battistella E, Jiang N, Rohlicek C, Shlyakhter I, Popic V.   +4 more
europepmc   +1 more source

Cell surface CD11c as a neutrophil aging marker molecule

FEBS Open Bio, EarlyView.
Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki, Fahd Alhamdan, Erik Malm, Marie Bermudez, Samuel Y. Kim, Koichi Yuki   +5 more
wiley   +1 more source

The C‐terminal domain of yeast Arginyltransferase1 is essential for its catalytic activity

FEBS Open Bio, EarlyView.
Arginyltransferase 1 (Ate1), a eukaryotic enzyme, catalyses arginylation, transferring arginine from tRNA‐Arg to the amino terminus of the target protein. Overexpression of Ate1 in yeast is lethal and is dependent on arginylation. This study elucidates how mutations in the cofactor‐binding and active site of Ate1 and truncation of its structural ...
Vikas Kumar Yadav, Shweta Shweta, Manisha Malhotra, Vikash Maurya, Akhilesh Kumar   +4 more
wiley   +1 more source

Pangenomic structural variant patterns reflect evolutionary diversification in Brassica napus. [PDF]

Genome Biol
Afsharyan NP, Golicz AA, Snowdon RJ.
europepmc   +1 more source

Genetic dissection of human ABCE1 in yeast reveals separable requirements for ribosome recycling and suppression of aberrant reinitiation

FEBS Open Bio, EarlyView.
Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata, Yuxin Li, Kei Endo, Koichi Ito   +3 more
wiley   +1 more source

The editable landscape of the yeast genome reveals hotspots of structural variant formation. [PDF]

Sci Adv
Li S, Vonesch SC, Roy KR, Tu CS, Steudle F, Nguyen M, Jann C, Steinmetz LM.   +7 more
europepmc   +1 more source

Evaluating GenAI‐produced feedback on undergraduate bioscience essays against good higher education feedback practice

FEBS Open Bio, EarlyView.
This pilot study investigates the potential of Generative AI to provide formative feedback to students. ChatGPT was prompted to provide feedback on Year 1 Bioscience essays, which were evaluated against established good feedback practices. GenAI‐authored feedback had useful elements, but was limited in scope. GenAI may have potential to provide instant,
Annabel Court, Nigel Francis, Andrew Shore, Stephen Rutherford   +3 more
wiley   +1 more source

A Structural Variant in the 5' Regulatory Region of <i>DIAPH3</i> Segregates with Postlingual Hearing Loss and Auditory Neuropathy in a Multigenerational Brazilian Family. [PDF]

Int Arch Otorhinolaryngol
Lezirovitz K, Alencar-Coutinho D, Diogo-Cavassana S, Abreu-Oberhuber R, Sampaio-Silva J, Paramo-Neto ME, Mingroni-Netto RC, Taguchi CK, Santos-Junior RC, Batissoco AC, Oiticica J, Bento RF.   +11 more
europepmc   +1 more source

Determinants of undergraduate bioscience engagement: Validating attendance barriers and classroom spatial behaviour across institutions

FEBS Open Bio, EarlyView.
Student engagement extends beyond simple attendance. Across 891 bioscience students from three universities, attendance behaviour was associated mainly with structural influences, whereas classroom spatial behaviour reflected affective and sensory factors.
Nigel Page, Rachel J. Hunt, Lauren J. Albee, Daniel Berwick, Alison Snape   +4 more
wiley   +1 more source

P636: Implementing structural variant analysis in Codicem: A comprehensive clinical variant analysis platform*

Genetics in Medicine Open
James Lawlor, Fariba ShaterFerdosian, Jacob Kelly, Wayne Schroer, Susan Hiatt, Ghunwa Nakouzi, Scott Newberry, Gregory Cooper   +7 more
doaj   +1 more source