Results 111 to 120 of about 2,462,103 (310)

Identification and Analysis of the TPS Gene Family in the Camellia sinensis Pan-Genome

Horticulturae
Terpene synthases (TPSs) are key enzymes in plant terpenoid biosynthesis and play important roles in growth and environmental responses. Here, we analyzed 22 high-quality Camellia sinensis pan-genomes to characterize the TPS gene family at the pan-genome
Jing Liu, Jiuju Luo, Kunbo Wang, Haojing Shao   +3 more
doaj   +1 more source

Welfare States, Social Structure and the Dynamics of Poverty Rates. A comparative study of 16 countries, 1980-2000. [PDF]

The purpose of this paper is twofold. The primary purpose is to try and explain both the temporal and the spatial variation of poverty rates in terms of unemployment insurance indicators and structural/sociodemographic factors.
Bäckman, Olof
core  

Freezing and melting of 3D complex plasma structures under microgravity conditions driven by neutral gas pressure manipulation

, 2011
Freezing and melting of large three-dimensional complex plasmas under microgravity conditions is investigated. The neutral gas pressure is used as a control parameter to trigger the phase changes: Complex plasma freezes (melts) by decreasing (increasing)
Fortov, V. E., Huber, P., Ivlev, A. V., Khrapak, S. A., Klumov, B. A., Lipaev, A. M., Malentschenko, Yu., Molotkov, V. I., Morfill, G. E., Naumkin, V. N., Petrov, O. F., Thomas, H. M., Volkov, S.   +12 more
core   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Differences in Pigment Content and Expression of Cocoon Color Formation-Related Genes in Multiple Silkworm Strains

Insects
Deciphering the coloration mechanism of natural-colored cocoons in the domestic silkworm (Bombyx mori) is of great importance for the green and sustainable development of the sericulture industry.
Lin Zhu, Mengli Li, Zijian Huang, Yuyang Wu, Guodong Zhao, Heying Qian   +5 more
doaj   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Origins, Dispersal, and Impact: Bidirectional Introgression Between Chinese and European Pig Populations

Advanced Science
Human mediated intra‐continental exchange of genetic material among domesticated organisms has never been restricted to a single direction. The introduction of pig breeds between China and Europe aims to enhance economically important traits in local ...
Yibin Qiu, Langqing Liu, Min Huang, Donglin Ruan, Rongrong Ding, Zebin Zhang, Enqin Zheng, Shiyuan Wang, Shaoxiong Deng, Xianglun Meng, Xinyan Cheng, Jiaxin Shi, Yingshan Yang, Fuchen Zhou, Sixiu Huang, Huaqiang Yang, Zicong Li, Gengyuan Cai, Zhenfang Wu, Jie Yang   +19 more
doaj   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

A Functional InDel in the WRKY10 Promoter Controls the Degree of Flesh Red Pigmentation in Apple

Advanced Science
MYB transcription factors have been linked to anthocyanin synthesis and various color phenotypes in plants. In apple, MYB10 confers a red‐flesh phenotype due to a minisatellite insertion in its R6 promoter, but R6:MYB10 genotypes exhibit various degrees ...
Nan Wang, Wenjun Liu, Zhuoxin Mei, Shuhui Zhang, Qi Zou, Lei Yu, Shenghui Jiang, Hongcheng Fang, Zongying Zhang, Zijing Chen, Shujing Wu, Lailiang Cheng, Xuesen Chen   +12 more
doaj   +1 more source