Results 171 to 180 of about 10,109,694 (374)

Properties of Relationships among objects in Object-Oriented Software Design [PDF]

open access: yesarXiv, 2015
One of the modern paradigms to develop a system is object oriented analysis and design. In this paradigm, there are several objects and each object plays some specific roles. After identifying objects, the various relationships among objects must be identified. This paper makes a literature review over relationships among objects.
arxiv  

The Term Structure of Interest Rates and Monetary Policy during a Zero Interest Rate Period [PDF]

open access: yes
This paper empirically evaluates the validity of the term structure of interest rates in a low interest rate environment using high-frequency Japanese data.
Nagayasu, Jun
core  

Electron Transfer-oxy Radical Mechanism for Anti-cancer Agents: 9-anilinoacridines [PDF]

open access: yes, 1987
A possible mode of action involving electron transfer is advanced for the 9- anilinoacridines. The mechanism entails formation of toxic oxy radicals which destroy the neoplasm.
Ames, James R.   +2 more
core   +1 more source

Bioengineering facets of the tumor microenvironment in 3D tumor models: insights into cellular, biophysical and biochemical interactions

open access: yesFEBS Open Bio, EarlyView.
The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik   +3 more
wiley   +1 more source

Research Progress of Natural Active Substances with Immunosuppressive Activity

open access: yesMolecules
The increasing prevalence of autoimmune diseases globally has prompted extensive research and the development of immunosuppressants. Currently, immunosuppressive drugs such as cyclosporine, rapamycin, and tacrolimus have been utilized in clinical ...
Fei Shao   +7 more
doaj   +1 more source

Synthesis and structure–activity relationship studies of teixobactin analogues

open access: yes, 2017
A new series of teixobactin analogues were synthesized via an oxidative cyclative cleavage approach using aryl hydrazide resin as the solid support. Structure–activity relationship studies revealed that the guanidine or amine group at position 10, the ...
Chunlei Wu   +5 more
semanticscholar   +1 more source

On subcellular distribution of the zinc finger 469 protein (ZNF469) and observed discrepancy in the localization of endogenous and overexpressed ZNF469

open access: yesFEBS Open Bio, EarlyView.
ZNF469 regulates the expression of genes encoding extracellular matrix proteins. Endogenous ZNF469 is predominantly cytoplasmic, while in transfected cells, it forms aggregates reminiscent of biomolecular condensates, located mainly in the nucleus. These condensates exhibit overlapping staining with proteasomes and are also associated with the mitotic ...
Anne Elisabeth Christensen Mellgren   +8 more
wiley   +1 more source

A randomized trial in a massive online open course shows people don't know what a statistically significant relationship looks like, but they can learn [PDF]

open access: yesarXiv, 2014
Scatterplots are the most common way for statisticians, scientists, and the public to visually detect relationships between measured variables. At the same time, and despite widely publicized controversy, P-values remain the most commonly used measure to statistically justify relationships identified between variables.
arxiv  

Home - About - Disclaimer - Privacy