Results 151 to 160 of about 17,696,992 (301)

Structure-Activity Relationship for Inflammasome Inhibition by Thiomuscimol. [PDF]

Int J Mol Sci
Anderson MJ, Loomis WP, den Hartigh AB, Frølund B, Fink SL.   +4 more
europepmc   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Classification, Structure-Activity Relationship, and Anti-Osteoarthritis Mechanism of Natural Flavonoids. [PDF]

Chem Biodivers
Wang H, Zheng S, Hua C, Feng W, Liu Z, Sun Y, Li M.   +6 more
europepmc   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source

A Structure-Activity Relationship Study of Trypargine and Opacaline β-Carbolines. [PDF]

Mar Drugs
Chen D, Rouvier F, Brunel JM, Copp BR, Cadelis MM.   +4 more
europepmc   +1 more source

The Term Structure of Interest Rate as a Predictor of Inflation and Real Economic Activity: Nonlinear Evidence from Turkey [PDF]

This study investigates whether the term structure of interest rates contains useful information about future real economic activity and inflation in Turkey during the 1991:7-2004:3 periods.
Omay, Tolga
core  

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

FEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan, Ikram A. Burney, Shika Hanif Malgundkar, Siva Ramamoorthy, Ressin Varghese, Mohamed A. Al‐Kindi, Hamad Al Riyami, Shadia Al Bahlani, Sergey Dobretsov, Syed Imran Hassan, Benjamin K. Tsang, Yahya Tamimi   +11 more
wiley   +1 more source

Structure-Activity Relationship Study of Antimalarial Asparagine-Derived Proteasome Inhibitors. [PDF]

ACS Omega
Zhang H, Li D, Hsu HC, Vishwanatha A, Zhan W, Yukawa T, Visone J, Imaeda T, Okamoto R, Fajtova P, Hara R, Kawasaki M, Sato K, Michino M, Garg S, Kreutzfeld O, Tumwebaze PK, Orena S, Okitwi M, Aso K, Cooper RA, Rosenthal PJ, Meinke PT, Foley M, O'Donoghue AJ, Li H, Kirkman LA, Lin G.   +27 more
europepmc   +1 more source

Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription

FEBS Open Bio, EarlyView.
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang, Mingqiang Deng, Dongmei He, Diqin Lai, Dongjun Liu, Dengyong Zhu, Zhenhua Zhang, Peng Tang, Chuanman Zhou, Menghui Yin, Xichen Bao   +10 more
wiley   +1 more source

Structure-Activity Relationship of Cycling Molecular Assemblies for Golgi Targeting and Disruption. [PDF]

J Med Chem
Tan W, Zhang Q, Hong P, Xu B.
europepmc   +1 more source