Results 11 to 20 of about 3,625,864 (333)

The relationship between redox enzyme activity and electrochemical potential—cellular and mechanistic implications from protein film electrochemistry [PDF]

, 2011
In protein film electrochemistry a redox protein of interest is studied as an electroactive film adsorbed on an electrode surface. For redox enzymes this configuration allows quantification of the relationship between catalytic activity and ...
Ackrell, Anderson, Anderson, Andrew G. Mayes, Andrew J. Gates, Angove, Armstrong, Armstrong, Armstrong, Armstrong, Armstrong, Arnoux, Bamford, Bekker, Berks, Blumberger, Blumberger, Buc, Butler, Butler, Chun Yip To, Clarke, Costa, David J. Richardson, Davis, de Vries, Dementin, Dias, Dridge, Eddowes, Ellington, Elliott, Field, Flores, Fourmond, Fourmond, Fourmond, Frangioni, Frew, Gates, Gates, Gemma L. Kemp, Georgellis, Gwyer, Hagedoorn, Hanson, Healy, Heering, Hirst, Hofmann, Hunte, Immoos, Ivanov, James Mann, Jepson, Jepson, Jeuken, Julea N. Butt, Kell, Kemp, Lin, Léger, Léger, Léger, Marritt, Marsili, Moore, Murgida, Niki, Otten, Otten, Page, Pershad, Potter, Ramirez, Richardson, Ridnour, Sears, Sears, Simons, Sophie J. Marritt, Sun, Tenderholt, Tenderholt, Thauer, Tipmanee, Wang, Westerhoff, Yeh, Zuman   +89 more
core   +1 more source

Structure-activity relationships of 3-substituted-5,5- diphenylhydantoins as potential antiproliferative and antimicrobial agents [PDF]

Journal of the Serbian Chemical Society, 2011
A series of twelve 3-substituted-5,5-diphenylhydantoins was synthesized, including some whose anticonvulsant activities have already been reported in the literature.
Trišović Nemanja, Marković Snežana, Čomić Ljiljana, Božić Biljana, Ušćumlić Gordana, Stefanović Olgica, Božić Bojan, Obradović Ana   +7 more
doaj   +1 more source

Application of Hansch’s Model to Capsaicinoids and Capsinoids: A Study Using the Quantitative Structure−Activity Relationship. A Novel Method for the Synthesis of Capsinoids [PDF]

, 2010
We describe a synthetic approach for two families of compounds, the capsaicinoids and capsinoids, as part of a study of the quantitative relationship between structure and ...
Appendino G., Barbero G. F., Barbero G. F., Bennett D. J., Careaga M., Chou J., Constant H. L., Gannett P. M., Hancock C. R., Henderson D. E., Iwai K., Kaga H., Kagan I. A., Kim C. S., Kobata K., Kobata K., Lipinski C. A., Macho A., Macias F. A., Mannhold R., Morris G. C., Nitsch J. P., Ohnuki K., Ohnuki K., Perucka I., Rekker R. F., Rosa A., Sancho R., Surh Y. J., Sutoh K., Torregiani E., Unnikrishnan M. C., Zewdie Y.   +32 more
core   +3 more sources

Vitamin K catabolite inhibition of ovariectomy-induced bone loss: Structure–activity relationship considerations [PDF]

, 2014
The potential benefit of vitamin K as a therapeutic in osteoporosis is controversial and the vitamin K regimen being used clinically (45 mg/day) employs doses that are many times higher than required to ensure maximal gamma‐carboxylation of the vitamin K‐
Emery, R, Hodges, S J, Imperial College London, Oguz, C, Pitsillides, A A, Soper, R J   +5 more
core   +1 more source

Structure-activity relationships of estrogens.

Environmental Health Perspectives, 1985
The last 50 years has seen an exponential rise in the published reports about estrogen action. The model to describe the early events in the mechanism of action of estrogens via the estrogen receptor is updated in this paper to incorporate some of the recent data on the subcellular localization of the receptor.
V C, Jordan, S, Mittal, B, Gosden, R, Koch, M E, Lieberman   +4 more
openaire   +2 more sources

Investigating the Structure–Activity Relationship of the Insecticidal Natural Product Rocaglamide

CHIMIA, 2017
The natural product Rocaglamide (1), isolated from the tree Aglaia elliptifolia, is a compelling but also challenging lead structure for crop protection.
Roger G. Hall, Ian Bruce, Nigel G. Cooke, Louis J. Diorazio, Fredrik Cederbaum, Markus R. Dobler, Ed Irving   +6 more
doaj   +1 more source

Synthesis and Fungicidal Activity of β-Carboline Alkaloids and Their Derivatives

Molecules, 2015
A series of β-Carboline derivatives were designed, synthesized, and evaluated for their fungicidal activities in this study. Several derivatives electively exhibited fungicidal activities against some fungi.
Zhibin Li, Shaohua Chen, Shaowen Zhu, Jianjun Luo, Yaomou Zhang, Qunfang Weng   +5 more
doaj   +1 more source

Synthesis and Antibacterial Evaluation of N-phenylacetamide Derivatives Containing 4-Arylthiazole Moieties

Molecules, 2020
A series of new N-phenylacetamide derivatives containing 4-arylthiazole moieties was designed and synthesized by introducing the thiazole moiety into the amide scaffold.
Hui Lu, Xia Zhou, Lei Wang, Linhong Jin
doaj   +1 more source

Design, Synthesis, and Anti-Inflammatory Activities of 12-Dehydropyxinol Derivatives

Molecules, 2023
Pyxinol skeleton is a promising framework of anti-inflammatory agents formed in the human liver from 20S-protopanaxadiol, the main active aglycone of ginsenosides. In the present study, a new series of amino acid-containing derivatives were produced from
Yunxiao Wang, Xiaoliang Mi, Yuan Du, Shuang Li, Liping Yu, Meng Gao, Xiaoyue Yang, Zhihua Song, Hui Yu, Gangqiang Yang   +9 more
doaj   +1 more source

A Remarkable Difference in Pharmacokinetics of Fluorinated Versus Iodinated Photosensitizers Derived from Chlorophyll-a and a Direct Correlation between the Tumor Uptake and Anti-Cancer Activity

Molecules, 2023
To investigate and compare the pharmacokinetic profile and anti-cancer activity of fluorinated and iodinated photosensitizers (PSs), the 3-(1′-(o-fluorobenzyloxy)ethyl pyropheophorbide and the corresponding meta-(m-) and para (p-) fluorinated analogs ...
Taur Prakash Pandurang, Joseph Cacaccio, Farukh A. Durrani, Mykhaylo Dukh, Ajyal Z. Alsaleh, Munawwar Sajjad, Francis D’Souza, Dalip Kumar, Ravindra K. Pandey   +8 more
doaj   +1 more source