Results 11 to 20 of about 971,232 (264)
Molecules, 2023 To investigate and compare the pharmacokinetic profile and anti-cancer activity of fluorinated and iodinated photosensitizers (PSs), the 3-(1′-(o-fluorobenzyloxy)ethyl pyropheophorbide and the corresponding meta-(m-) and para (p-) fluorinated analogs ...
Taur Prakash Pandurang +8 more
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Structure-activity relationships of estrogens.
Environmental Health Perspectives, 1985 The last 50 years has seen an exponential rise in the published reports about estrogen action. The model to describe the early events in the mechanism of action of estrogens via the estrogen receptor is updated in this paper to incorporate some of the recent data on the subcellular localization of the receptor.
V C, Jordan +4 more
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Investigating the Structure–Activity Relationship of the Insecticidal Natural Product Rocaglamide
CHIMIA, 2017 The natural product Rocaglamide (1), isolated from the tree Aglaia elliptifolia, is a compelling but also challenging lead structure for crop protection.
Roger G. Hall +6 more
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Synthesis and Fungicidal Activity of β-Carboline Alkaloids and Their Derivatives
Molecules, 2015 A series of β-Carboline derivatives were designed, synthesized, and evaluated for their fungicidal activities in this study. Several derivatives electively exhibited fungicidal activities against some fungi.
Zhibin Li +5 more
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Molecules, 2020 A series of new N-phenylacetamide derivatives containing 4-arylthiazole moieties was designed and synthesized by introducing the thiazole moiety into the amide scaffold.
Hui Lu, Xia Zhou, Lei Wang, Linhong Jin
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Design, Synthesis, and Anti-Inflammatory Activities of 12-Dehydropyxinol Derivatives
Molecules, 2023 Pyxinol skeleton is a promising framework of anti-inflammatory agents formed in the human liver from 20S-protopanaxadiol, the main active aglycone of ginsenosides. In the present study, a new series of amino acid-containing derivatives were produced from
Yunxiao Wang +9 more
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CHIMIA, 2017 Malaria is one of the leading infectious diseases occurring mainly in tropical and subtropical areas. Although available antimalarial tools have reduced the number of fatalities, there is still an urgent need for the development of new and more ...
Fabian Brockmeyer, Roman Manetsch
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Pyrimidine: a review on anticancer activity with key emphasis on SAR
Future Journal of Pharmaceutical Sciences, 2021 Background Cancer is a global health challenge, it impacts the quality of life and its treatment is associated with several side effects. Resistance of the cancer cells to the existing drugs has led to search for novel anticancer agents.
Aastha Mahapatra +2 more
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Journal of Enzyme Inhibition and Medicinal Chemistry, 2021 Inflammation and disease are closely related. Inflammation can induce various diseases, and diseases can promote inflammatory response, and two possibly induces each other in a bidirectional loop.
Ming Bian +4 more
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An Insight into Antihyperlipidemic Effects of Polysaccharides from Natural Resources
Molecules, 2022 Hyperlipidemia is a chronic metabolic disease caused by the abnormal metabolism of lipoproteins in the human body. Its main hazard is to accelerate systemic atherosclerosis, which causes cerebrovascular diseases such as coronary heart disease and ...
Yong-Shuai Jing +6 more
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