Results 21 to 30 of about 5,621,217 (307)

Relationship Between the Structure and Immune Activity of Components From the Active Polysaccharides APS-II of Astragali Radix by Enzymolysis of Endo α-1,4-Glucanase

Frontiers in Pharmacology, 2022
Astragali Radix polysaccharides (APSs) have a wide range of biological activities. Our preliminary experiment showed that APS-Ⅱ (10 kDa) was the main immunologically active component of APSs.
Ke Li, Ke Li, Ke Li, Ke Li, Xue-qin Li, Xue-qin Li, Xue-qin Li, Guang-xin Li, Lian-jie Cui, Lian-jie Cui, Lian-jie Cui, Xue-mei Qin, Xue-mei Qin, Xue-mei Qin, Zhen-yu Li, Zhen-yu Li, Zhen-yu Li, Yu-guang Du, Yue-tao Liu, Yue-tao Liu, Yue-tao Liu, Ai-ping Li, Ai-ping Li, Ai-ping Li, Xing-yun Zhao, Xing-yun Zhao, Xing-yun Zhao, Xin-hui Fan, Xin-hui Fan, Xin-hui Fan   +29 more
doaj   +1 more source

A Remarkable Difference in Pharmacokinetics of Fluorinated Versus Iodinated Photosensitizers Derived from Chlorophyll-a and a Direct Correlation between the Tumor Uptake and Anti-Cancer Activity

Molecules, 2023
To investigate and compare the pharmacokinetic profile and anti-cancer activity of fluorinated and iodinated photosensitizers (PSs), the 3-(1′-(o-fluorobenzyloxy)ethyl pyropheophorbide and the corresponding meta-(m-) and para (p-) fluorinated analogs ...
Taur Prakash Pandurang, Joseph Cacaccio, Farukh A. Durrani, Mykhaylo Dukh, Ajyal Z. Alsaleh, Munawwar Sajjad, Francis D’Souza, Dalip Kumar, Ravindra K. Pandey   +8 more
doaj   +1 more source

Structure-functional activity relationship of β-glucans from the perspective of immunomodulation : a mini-review [PDF]

, 2020
β-Glucans are a heterogeneous group of glucose polymers with a common structure comprising a main chain of β-(1,3) and/or β-(1,4)-glucopyranosyl units, along with side chains with various branches and lengths.
Baruah, Sri Kartik, Bossier, Peter, Cox, Eric, Han, Biao, Vanrompay, Daisy   +4 more
core   +2 more sources

Structure - Activity Relationship of Mutant KatG from INH resistant Mycobacterium tuberculosis

Journal of Pure and Applied Microbiology, 2017
Mutation in katG gene of Mycobacterium tuberculosis encoding catalase-peroxidase that damage its enzyme activities is well associated with isoniazid (INH) resistance. The katG gene from INH resistant strain of M.
Purkan Purkan, Sri Puji Astuti Wahyuningsih, Wiwin Retnowati, Diah Amelia, Alfain Noerdin Alimny   +4 more
doaj   +1 more source

Structure and permeability of ion-channels by integrated AFM and waveguide TIRF microscopy. [PDF]

, 2014
Membrane ion channels regulate key cellular functions and their activity is dependent on their 3D structure. Atomic force microscopy (AFM) images 3D structure of membrane channels placed on a solid substrate.
Arce, Fernando Teran, Cohen, Daniel A, Lal, Ratnesh, Patel, Nirav R, Quist, Arjan P, Ramachandran, Srinivasan   +5 more
core   +2 more sources

Structure-activity relationships of 3-substituted-5,5- diphenylhydantoins as potential antiproliferative and antimicrobial agents [PDF]

Journal of the Serbian Chemical Society, 2011
A series of twelve 3-substituted-5,5-diphenylhydantoins was synthesized, including some whose anticonvulsant activities have already been reported in the literature.
Trišović Nemanja, Marković Snežana, Čomić Ljiljana, Božić Biljana, Ušćumlić Gordana, Stefanović Olgica, Božić Bojan, Obradović Ana   +7 more
doaj   +1 more source

Structure-activity relationships of the nikkomycins [PDF]

Journal of General Microbiology, 1991
The structure-activity relationships of different nikkomycins were studied to evaluate the structural requirements for a potent chitin synthase inhibitor. We investigated the transport of the nikkomycins via the peptide transport system of the yeast Yarrowia lipolytica and determined the kinetic parameters for nikkomycin Z uptake [Km = 24 microM, Vmax =
H. Heitsch, H.-P. Fiedler, Wilfried A. König, Hans Zähner, Heinrich Decker   +4 more
openaire   +3 more sources

The relationship between redox enzyme activity and electrochemical potential—cellular and mechanistic implications from protein film electrochemistry [PDF]

, 2011
In protein film electrochemistry a redox protein of interest is studied as an electroactive film adsorbed on an electrode surface. For redox enzymes this configuration allows quantification of the relationship between catalytic activity and ...
Ackrell, Anderson, Anderson, Andrew G. Mayes, Andrew J. Gates, Angove, Armstrong, Armstrong, Armstrong, Armstrong, Armstrong, Arnoux, Bamford, Bekker, Berks, Blumberger, Blumberger, Buc, Butler, Butler, Chun Yip To, Clarke, Costa, David J. Richardson, Davis, de Vries, Dementin, Dias, Dridge, Eddowes, Ellington, Elliott, Field, Flores, Fourmond, Fourmond, Fourmond, Frangioni, Frew, Gates, Gates, Gemma L. Kemp, Georgellis, Gwyer, Hagedoorn, Hanson, Healy, Heering, Hirst, Hofmann, Hunte, Immoos, Ivanov, James Mann, Jepson, Jepson, Jeuken, Julea N. Butt, Kell, Kemp, Lin, Léger, Léger, Léger, Marritt, Marsili, Moore, Murgida, Niki, Otten, Otten, Page, Pershad, Potter, Ramirez, Richardson, Ridnour, Sears, Sears, Simons, Sophie J. Marritt, Sun, Tenderholt, Tenderholt, Thauer, Tipmanee, Wang, Westerhoff, Yeh, Zuman   +89 more
core   +1 more source

Structure-activity relationship in monosaccharide-based Toll-like receptor 4 (TLR4) antagonists [PDF]

, 2018
The structure-activity relationship was investigated in a series of synthetic TLR4 antagonists formed by a glucosamine core linked to two phosphate esters and two linear carbon chains.
Airoldi, Cristina, Beyaert, Rudi, Billod, Jean-Marc, Braun, Harald, Calabrese, Valentina, Ciaramelli, Carlotta, Facchini, Fabio A, Forcella, Matilde, Fusi, Paola, Jerala, Roman, Lapenta, Fabio, Martin-Santamaria, Sonsoles, Minotti, Alberto, Palmer, Charys, Peri, Francesco, Pirianov, Grisha, Rapisarda, Silvia, Schromm, Andra B, Zaffaroni, Lenny   +18 more
core   +3 more sources

Antibacterial Properties of Polyphenols: Characterization and QSAR (Quantitative Structure–Activity Relationship) Models

Frontiers in Microbiology, 2019
Besides their established antioxidant activity, many phenolic compounds may exhibit significant antibacterial activity. Here, the effect of a large dataset of 35 polyphenols on the growth of 6 foodborne pathogenic or food-spoiling bacterial strains ...
Lynda Bouarab-Chibane, V. Forquet, P. Lanteri, Y. Clément, Lucie Léonard-Akkari, N. Oulahal, P. Degraeve, C. Bordes   +7 more
semanticscholar   +1 more source