Results 81 to 90 of about 5,731,208 (381)
A New Kind of Quinonic-Antibiotic Useful Against Multidrug-Resistant S. aureus and E. faecium Infections [PDF]
, 2018 Indexación: Scopus.A rapid emergence of resistant bacteria is occurring worldwide, endangering the efficacy of antibiotics and reducing the therapeutic arsenal available for treatment of infectious diseases. In the present study, we developed a new class
Alarcón, P. +13 more
core +1 more source
Shipin gongye ke-jiDendrobium is a traditional, valuable, and nourishing medicinal herb in China. It benefits the stomach, promotes fluid production, nourishes Yin, and clears heat. Polysaccharides are among the main active ingredients of Dendrobium.
Zhaoyong LUO +7 more
doaj +1 more source
Single‐cell insights into the role of T cells in B‐cell malignancies
FEBS Letters, EarlyView.Single‐cell technologies have transformed our understanding of T cell–tumor cell interactions in B‐cell malignancies, revealing new T‐cell subsets, functional states, and immune evasion mechanisms. This Review synthesizes these findings, highlighting the roles of T cells in pathogenesis, progression, and therapy response, and underscoring their ...
Laura Llaó‐Cid
wiley +1 more source
Structure-activity relationship studies on O-sulfated Hirudins [PDF]
, 1998 Thesis (Ph. D. in Agriculture)--University of Tsukuba, (B), no.
Muramatsu Ryo, 村松 了
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Electrochemical behavior of indolone-N-oxides: Relationship to structure and antiplasmodial activity [PDF]
, 2012 Indolone-N-oxides exert high parasiticidal activity at the nanomolar level in vitro against Plasmodiumfalciparum, the parasite responsible for malaria.
Fabre, Paul-Louis +6 more
core +3 more sources
Biotechnology & Biotechnological Equipment, 2020 Dechlorination is the key step in biological degradation of dichloromethane (DCM), which is catalyzed by the enzyme DCM dehalogenase. In this study, the detailed structure and function of DCM dehalogenase in Methylobacterium rhodesianum H13 were ...
Jianguo Ni +5 more
doaj +1 more source
FEBS Letters, EarlyView.Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu +17 more
wiley +1 more source
A practical overview of quantitative structure-activity relationship [PDF]
, 2009 Quantitative structure-activity relationship (QSAR) modeling pertains to the construction of predictive models of biological activities as a function of structural and molecular information of a compound library.
Isarankura-Na-Ayudhya, Chartchalerm +3 more
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Inferring Synaptic Structure in presence of Neural Interaction Time Scales [PDF]
, 2015 Biological networks display a variety of activity patterns reflecting a web of interactions that is complex both in space and time. Yet inference methods have mainly focused on reconstructing, from the network's activity, the spatial structure, by ...
Capone, Cristiano +4 more
core +4 more sources
Structure–activity relationship of amyloid fibrils [PDF]
FEBS Letters, 2009 Protein aggregation is a process in which proteins self‐associate into imperfectly ordered macroscopic entities. Such aggregates are generally classified as either amorphous or highly ordered, the most common form of the latter being amyloid fibrils. Amyloid fibrils composed of cross‐β‐sheet structure are the pathological hallmarks of several diseases ...
Jason Greenwald +3 more
openaire +3 more sources